Platelet‐activation mechanisms and vascular remodeling

DA Rubenstein, W Yin - Comprehensive Physiology, 2011 - Wiley Online Library
This overview article for the Comprehensive Physiology collection is focused on detailing
platelets, how platelets respond to various stimuli, how platelets interact with their external …

Mathematical and computational modeling of device-induced thrombosis

KB Manning, F Nicoud, SM Shea - Current opinion in biomedical …, 2021 - Elsevier
Given the extensive and routine use of cardiovascular devices, a major limiting factor to their
success is the thrombotic rate that occurs. This poses direct risk to the patient and requires …

Feasibility of an implantable bioreactor for renal cell therapy using silicon nanopore membranes

EJ Kim, C Chen, R Gologorsky, A Santandreu… - Nature …, 2023 - nature.com
The definitive treatment for end-stage renal disease is kidney transplantation, which remains
limited by organ availability and post-transplant complications. Alternatively, an implantable …

Computational design of a soft robotic myocardium for biomimetic motion and function

C Park, C Ozturk, ET Roche - Advanced Functional Materials, 2022 - Wiley Online Library
Soft robotic devices containing multiple actuating elements have successfully recapitulated
complex biological motion, leading to their utility in biomedical applications. However, there …

Association of vortical structures and hemodynamic parameters for regional thrombus accumulation in abdominal aortic aneurysms

BA Zambrano, H Gharahi, CY Lim… - … journal for numerical …, 2022 - Wiley Online Library
The intraluminal thrombus (ILT) has been shown to negatively impact the progression of the
abdominal aortic aneurysms (AAAs). The formation of this thrombus layer has been …

[HTML][HTML] Role of surgeon intuition and computer-aided design in Fontan optimization: A computational fluid dynamics simulation study

YH Loke, B Kim, P Mass, JD Opfermann… - The Journal of thoracic …, 2020 - Elsevier
Abstract Objective Customized Fontan designs, generated by computer-aided design (CAD)
and optimized by computational fluid dynamics simulations, can lead to novel, patient …

Exploring hemodynamic mechanisms and re-intervention strategies for partial false lumen thrombosis in Stanford type B aortic dissection after thoracic aortic …

J Wang, B Chen, F Gao - International Journal of Cardiology, 2024 - Elsevier
Objectives False lumen (FL) thrombosis status for Stanford type B aortic dissection (TBAD)
after thoracic endovascular aortic repair (TEVAR) is critical for evaluating aortic remodeling …

[HTML][HTML] Virtual reality cardiac surgical planning software (CorFix) for designing patient-specific vascular grafts: development and pilot usability study

B Kim, P Nguyen, YH Loke, V Cleveland, X Liu… - JMIR cardio, 2022 - cardio.jmir.org
Background: Patients with single ventricle heart defects receive 3 stages of operations
culminating in the Fontan procedure. During the Fontan procedure, a vascular graft is …

In-silico enhanced animal study of pulmonary artery pressure sensors: assessing hemodynamics using computational fluid dynamics

J Brüning, P Yevtushenko, A Schlief… - Frontiers in …, 2023 - frontiersin.org
To assess whether in-silico models can be used to predict the risk of thrombus formation in
pulmonary artery pressure sensors (PAPS), a chronic animal study using pigs was …

Influence of distal re-entry tears on false lumen thrombosis after thoracic endovascular aortic repair in type B aortic dissection patients: a computational fluid dynamics …

D Li, T Zheng, Z Liu, Y Li, D Yuan, Y Fan - … Engineering and Technology, 2021 - Springer
Purpose Distal re-entry tears play a significant role in false lumen (FL) thrombosis, which will
strongly affect the postoperative long-term survival of patients with type B aortic dissection …