Naturally acquired immunity to falciparum malaria protects millions of people routinely
exposed to Plasmodium falciparum infection from severe disease and death. There is no …

Malaria is one of the most serious infectious diseases with most of the severe disease
caused by Plasmodium falciparum (Pf). Naturally acquired immunity develops over time after …

Neonates and infants are relatively protected from clinical malaria, but the mechanism of this
protection is not well understood. Maternally derived antibodies are commonly believed to …

Malarial anemia (MA) is a multifactorial disease for which the complex etiological basis is
only partially defined. The association of clinical, nutritional, demographic, and …

Background Antibody-mediated complement fixation has previously been associated with
protection against malaria in naturally acquired immunity. However, the process of early-life …

Background Naturally acquired malaria immunity has many determinants and, in the
absence of immunological markers of protection, studies assessing malaria incidence …

Background Plasmodium falciparum malaria is a leading cause of child mortality in Nigeria.
Neonates are born with maternal antibodies from placental transfer which may protect …

Malaria is a serious cause of morbidity and mortality for people living in endemic areas, but
unlike many other infections, individuals exposed to the parasite do not rapidly become …

Malaria is a vector-borne infectious disease caused by infection with eukaryotic pathogens
termed Plasmodium. Epidemiological hallmarks of Plasmodium falciparum malaria are …

The incidence of Plasmodium falciparum infection has been followed in a birth cohort of 71
infants in southern Ghana, an area of perennial malaria transmission. Parasite DNA …