CAR-T cell combination therapy: the next revolution in cancer treatment

M Al-Haideri, SB Tondok, SH Safa, AH Maleki… - Cancer Cell …, 2022 - Springer
In recent decades, the advent of immune-based therapies, most notably Chimeric antigen
receptor (CAR)-T cell therapy has revolutionized cancer treatment. The promising results of …

Novel therapeutic agents in clinical trials: emerging approaches in cancer therapy

DC Joshi, A Sharma, S Prasad, K Singh, M Kumar… - Discover Oncology, 2024 - Springer
Novel therapeutic agents in clinical trials offer a paradigm shift in the approach to battling
this prevalent and destructive disease, and the area of cancer therapy is on the precipice of …

CAR-T cell therapy for hematological malignancies: History, status and promise

C Wang, J Wang, S Che, H Zhao - Heliyon, 2023 - cell.com
For many years, the methods of cancer treatment are usually surgery, chemotherapy and
radiation therapy. Although these methods help to improve the condition, most tumors still …

Immunotherapy in acute myeloid leukemia: a literature review of emerging strategies

L Guarnera, C Bravo-Perez, V Visconte - Bioengineering, 2023 - mdpi.com
In the last twenty years, we have witnessed a paradigm shift in the treatment and prognosis
of acute myeloid leukemia (AML), thanks to the introduction of new efficient drugs or …

Chimeric Antigen Receptor T Cell Therapy for Hepatocellular Carcinoma: Where Do We Stand?

I Aggeletopoulou, M Kalafateli, C Triantos - International Journal of …, 2024 - mdpi.com
Hepatocellular carcinoma (HCC) remains a global health challenge that urgently calls for
innovative therapeutic strategies. Chimeric antigen receptor T cell (CAR T) therapy has …

Engineered T cells for Colorectal Cancer

NAA Rus Bakarurraini, AA Kamarudin, R Jamal… - …, 2024 - Taylor & Francis
Colorectal cancer (CRC) is a major contributor to global cancer incidence and mortality.
Conventional treatments have limitations; hence, innovative approaches are imperative …

Recent updates on chimeric antigen receptor T-cell approaches in cancer immunotherapy

M Sahlolbei, A Ahmadieh-Yazdi… - Advances in Cancer …, 2024 - books.google.com
Chimeric antigen receptor (CAR) T-cell therapy is a revolutionary development in the field of
cancer immunotherapy, offering a targeted approach to combat various hematologic …

Display of Polyvalent Hybrid Antibodies on the Cell Surface for Enhanced Cell Recognition

X Wang, Y Wang, K Lee, B Davis, C Wen, B Jia… - Small …, 2024 - Wiley Online Library
Cell surface engineering with exogeneous receptors holds great promise for various
applications. However, current biological methods face problems with safety, antigen …

An overview of the therapeutic strategies for neoplastic meningitis due to breast cancer: when and why?

M Bardhan, D Dey, V Suresh, B Javed… - Expert Review of …, 2024 - Taylor & Francis
Introduction Neoplastic meningitis (NM), also known as leptomeningeal carcinomatosis, is
characterized by the infiltration of tumor cells into the meninges, and poses a significant …

[HTML][HTML] Exploring CAR-PBMCs: A Novel Strategy Against EGFR-Positive Tumor Cells

A Tîrziu, OI Gavriliuc, MF Bojin, V Păunescu - Biomedicines, 2025 - mdpi.com
Background: Chimeric antigen receptor (CAR) T cell therapy has shown significant promise
in treating hematological malignancies, yet its application in solid tumors, particularly those …