Context Immunohistochemistry has assumed an increasing role in the identification and
characterization of gynecologic disorders including lesions with deceptively bland …

Within the last decade, molecular advances have provided insights into the genetics of
several ovarian sex cord–stromal tumours that have otherwise been enigmatic. Chief among …

Since our first description of the microcystic stromal tumor (MST) of the ovary, a rare and
distinctive neoplasm with a definitional, usually striking microcystic pattern and a …

Sertoli cell tumor (SCT) is the second most common type of sex cord-stromal tumor in men,
and∼ 10% exhibit malignant behavior. Although CTNNB1 variants have been described in …

The Sertoli cell tumor (SCT) of the testis is a sex cord stromal tumor, usually sporadic, rarely
associated with genetic syndromes. Much remains unclear about the molecular genetic …

New tumour types are being described at increasing frequency, and most new tumour types
are now identified via retrospective review of next-generation sequencing data. This …

1 CTNNB1: c. 95A> T, p. D32V Same mutation 2 CTNNB1: c. 104T> G, p. 135S Same
mutation 3 CTNNB1: c. 95A> T, p. D32V Same mutation 4 NEG (wild-type) CTNNB1: c …

The relative frequency of ovarian tumors and tumor-like lesions that occur in young females
(defined in this article as up to 30 years of age) differs considerably from that seen in older …

Ovarian microcystic stromal tumor (MCST) is a very rare neoplasm; hence, its nomenclature
was recently designated as “Distinctive morphologic and immunohistochemical features” in …

Simple Summary Liquid biopsy for cell-free DNA (cfDNA) is a non-invasive technique to
characterize the genetic profile of a tumor. Despite being a valuable tool, there is no …