Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

Cancer immunotherapy in the form of immune checkpoint inhibitors and cellular therapies
has improved the treatment and prognosis of many patients. Nevertheless, most cancers are …

Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the gut. There
is growing evidence in Crohn's disease (CD) of the existence of a preclinical period …

Colorectal cancer (CRC) represents the third most common malignancy and the second
leading cause of cancer-related deaths worldwide. Although immunotherapy has taken …

Hypoxia is an environmental stressor that is instigated by low oxygen availability. It fuels the
progression of solid tumors by driving tumor plasticity, heterogeneity, stemness and genomic …

As a subset of pattern recognition receptors (PRRs), C-type lectin-like receptors (CLRs) are
mainly expressed by myeloid cells as both transmembrane and soluble forms. CLRs …

Essentially all cells are covered with a dense coat of different glycan structures/sugar chains,
giving rise to the so‐called glycocalyx. Changes in cellular glycosylation are a hallmark of …

Recent evidence suggests that cancer cell-derived extracellular vesicles might facilitate
immunoevasion. Glycans are known to play a key role in immunomodulation, especially …

Glycans are carbohydrates that are made by all organisms and covalently conjugated to
other biomolecules. Glycans cover the surface of both human cells and pathogens and are …

Background Changes in protein glycosylation are widely observed in tumor cells. N-glycan
branching through adding β1, 6-linked N-acetylglucosamine (β1, 6-GlcNAc) to an α1, 6 …