Sponge-associated microorganisms: evolution, ecology, and biotechnological potential

MW Taylor, R Radax, D Steger… - … and molecular biology …, 2007 - Am Soc Microbiol
Marine sponges often contain diverse and abundant microbial communities, including
bacteria, archaea, microalgae, and fungi. In some cases, these microbial associates …

Nutrient fluxes through sponges: biology, budgets, and ecological implications

M Maldonado, M Ribes, FC van Duyl - Advances in marine biology, 2012 - Elsevier
Marine sponges are able to process a variety of carbon (C), nitrogen (N), phosphorous (P),
and silicon (Si) dissolved compounds, in addition to the particulate C, N, and P obtained …

The essentials of marine biotechnology

A Rotter, M Barbier, F Bertoni, AM Bones… - Frontiers In marine …, 2021 - frontiersin.org
Coastal countries have traditionally relied on the existing marine resources (eg, fishing,
food, transport, recreation, and tourism) as well as tried to support new economic endeavors …

Marine invertebrate metabolites with anticancer activities: Solutions to the “supply problem”

NGM Gomes, R Dasari, S Chandra, R Kiss… - Marine drugs, 2016 - mdpi.com
Marine invertebrates provide a rich source of metabolites with anticancer activities and
several marine-derived agents have been approved for the treatment of cancer. However …

Large‐scale production of pharmaceuticals by marine sponges: Sea, cell, or synthesis?

D Sipkema, R Osinga, W Schatton… - Biotechnology and …, 2005 - Wiley Online Library
Marine sponges are known to produce an overwhelming array of secondary metabolites
with pharmaceutical potential. The technical and economical potential of using marine …

Drugs from the sea: conopeptides as potential therapeutics

BG Livett, KR Gayler, Z Khalil - Current medicinal chemistry, 2004 - ingentaconnect.com
Marine cone snails from the genus Conus are estimated to consist of up to 700 species.
These predatory molluscs have devised an efficient venom apparatus that allows them to …

Sustainable production of biologically active molecules of marine based origin

PM Murray, S Moane, C Collins, T Beletskaya… - New …, 2013 - Elsevier
The marine environment offers both economic and scientific potential which are relatively
untapped from a biotechnological point of view. These environments whilst harsh are …

[HTML][HTML] Marine sponge aquaculture towards drug development: An ongoing history of technical, ecological, chemical considerations and challenges

M Maslin, N Gaertner-Mazouni, C Debitus, N Joy… - Aquaculture …, 2021 - Elsevier
Marine sponges have a long history of farming, starting with bath sponges over 5000 years
ago in the Mediterranean. Many species have since been found appropriate for distinct …

First continuous marine sponge cell line established

K Hesp, JME van der Heijden, S Munroe, D Sipkema… - Scientific Reports, 2023 - nature.com
The potential of sponge-derived chemicals for pharmaceutical applications remains largely
unexploited due to limited available biomass. Although many have attempted to culture …

Cultivation of sponges, sponge cells and symbionts: achievements and future prospects

KJ Schippers, D Sipkema, R Osinga, H Smidt… - Advances in marine …, 2012 - Elsevier
Marine sponges are a rich source of bioactive compounds with pharmaceutical potential.
Since biological production is one option to supply materials for early drug development, the …