Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine

B Nilius, A Szallasi - Pharmacological reviews, 2014 - ASPET
The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

Expert opinion on the cough hypersensitivity syndrome in respiratory medicine

AH Morice, E Millqvist, MG Belvisi… - European …, 2014 - Eur Respiratory Soc
In 2011, a European Respiratory Society Task Force embarked on a process to determine
the position and clinical relevance of the cough hypersensitivity syndrome, a disorder …

Recommendations for the management of cough in adults

AH Morice, L McGarvey, I Pavord - Thorax, 2006 - thorax.bmj.com
1.1 Background Patients with cough frequently present to clinicians working in both primary
and secondary care. 1, 2 Acute cough, which often follows an upper respiratory tract …

Exhaled markers of pulmonary disease

SA Kharitonov, PJ Barnes - … journal of respiratory and critical care …, 2001 - atsjournals.org
There has recently been an explosion of interest in the analysis of breath constituents as a
way of monitoring inflammation and oxidative stress in the lungs. Here we review the use of …

The diagnosis and management of chronic cough

AH Morice - European Respiratory Journal, 2004 - Eur Respiratory Soc
Background Chronic cough, here defined as a cough ofw8 weeks duration, is a common
and frequently debilitating symptom [1, 2] that is often viewed as an intractable problem …

Breath analysis: potential for clinical diagnosis and exposure assessment

W Cao, Y Duan - Clinical chemistry, 2006 - academic.oup.com
Breath tests are among the least invasive methods available for clinical diagnosis, disease
state monitoring, and environmental exposure assessment. In recent years, interest in breath …

Exhaled nitric oxide measurements: clinical application and interpretation

DR Taylor, MW Pijnenburg, AD Smith, JCD Jongste - Thorax, 2006 - thorax.bmj.com
The use of exhaled nitric oxide measurements (FEno) in clinical practice is now coming of
age. There are a number of theoretical and practical factors which have brought this about …

Chronic cough due to gastroesophageal reflux disease: ACCP evidence-based clinical practice guidelines

RS Irwin - Chest, 2006 - Elsevier
Objectives: To critically review and summarize the literature on cough and
gastroesophageal reflux disease (GERD), and to make evidence-based recommendations …

Biomarkers of some pulmonary diseases in exhaled breath

SA Kharitonov, PJ Barnes - Biomarkers, 2002 - Taylor & Francis
Analysis of various biomarkers in exhaled breath allows completely non-invasive monitoring
of inflammation and oxidative stress in the respiratory tract in inflammatory lung diseases …

Prospective evaluation of the validity of exhaled nitric oxide for the diagnosis of asthma

LJ Dupont, MG Demedts, GM Verleden - Chest, 2003 - Elsevier
Study objective Exhaled nitric oxide (NO) levels are significantly elevated in patients with
inflammatory airways disorders such as asthma, and the measurement of exhaled NO has …