[HTML][HTML] Adaptive optics imaging of the human retina

SA Burns, AE Elsner, KA Sapoznik, RL Warner… - Progress in retinal and …, 2019 - Elsevier
Adaptive Optics (AO) retinal imaging has provided revolutionary tools to scientists and
clinicians for studying retinal structure and function in the living eye. From animal models to …

Evolution of adaptive optics retinal imaging

DR Williams, SA Burns, DT Miller… - Biomedical Optics …, 2023 - opg.optica.org
This review describes the progress that has been achieved since adaptive optics (AO) was
incorporated into the ophthalmoscope a quarter of a century ago, transforming our ability to …

Twenty-five years of clinical applications using adaptive optics ophthalmoscopy

JIW Morgan, TYP Chui, K Grieve - Biomedical optics express, 2023 - opg.optica.org
Twenty-five years ago, adaptive optics (AO) was combined with fundus photography,
thereby initiating a new era in the field of ophthalmic imaging. Since that time, clinical …

[HTML][HTML] Vision science and adaptive optics, the state of the field

S Marcos, JS Werner, SA Burns, WH Merigan, P Artal… - Vision research, 2017 - Elsevier
Adaptive optics is a relatively new field, yet it is spreading rapidly and allows new questions
to be asked about how the visual system is organized. The editors of this feature issue have …

Imaging the retinal vasculature

SA Burns, AE Elsner, TJ Gast - Annual review of vision science, 2021 - annualreviews.org
Advances in retinal imaging are enabling researchers and clinicians to make precise
noninvasive measurements of the retinal vasculature in vivo. This includes measurements of …

Imaging single-cell blood flow in the smallest to largest vessels in the living retina

A Joseph, A Guevara-Torres, J Schallek - elife, 2019 - elifesciences.org
Tissue light scatter limits the visualization of the microvascular network deep inside the living
mammal. The transparency of the mammalian eye provides a noninvasive view of the …

Retinal blood velocity and flow in early diabetes and diabetic retinopathy using adaptive optics scanning laser ophthalmoscopy

CMA Palochak, HE Lee, J Song, A Geng… - Journal of clinical …, 2019 - mdpi.com
Using adaptive optics scanning laser ophthalmoscopy (AOSLO), we measured retinal blood
velocity and flow in healthy control eyes and eyes of diabetic patients with or without …

Computational investigation of blood cell transport in retinal microaneurysms

H Li, Y Deng, K Sampani, S Cai, Z Li… - PLoS Computational …, 2022 - journals.plos.org
Microaneurysms (MAs) are one of the earliest clinically visible signs of diabetic retinopathy
(DR). MA leakage or rupture may precipitate local pathology in the surrounding neural retina …

Noninvasive in vivo characterization of erythrocyte motion in human retinal capillaries using high-speed adaptive optics near-confocal imaging

B Gu, X Wang, MD Twa, J Tam, CA Girkin… - Biomedical Optics …, 2018 - opg.optica.org
The flow of erythrocytes in parafoveal capillaries was imaged in the living human eye with
an adaptive optics near-confocal ophthalmoscope at a frame rate of 800 Hz with a low …

The effect of stiffened diabetic red blood cells on wall shear stress in a reconstructed 3D microaneurysm

B Czaja, J de Bouter, M Heisler… - Computer Methods in …, 2022 - Taylor & Francis
Blood flow within the vasculature of the retina has been found to influence the progression of
diabetic retinopathy. In this research cell resolved blood flow simulations are used to study …