Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Osteosarcoma is a malignant bone tumor characterized by the direct production of osteoid
tissue from tumor cells. Extracellular vesicles are membranous vesicles released by cells …

Osteosarcoma (OS) is a primary bone cancer that is highly prevalent among adolescents
and adults below the age of 20 years. The prognostic outcome of metastatic OS or relapse is …

Polylactic acid (PLA) is a versatile and biodegradable scaffold widely used in biomedical
fields to repair tissue defects. Exosomes derived from mesenchymal stem cells (MSCs) are …

Osteosarcoma is a primary malignant tumor of the skeleton with the morbidity of 2.5 in 1
million. The regularly on-set is in the epiphysis of the extremities with a high possibility of …

Osteosarcoma, the most common primary malignant tumor of bone, occurs frequently in
teenagers and is the third most common type of cancer among children and adolescents …

Extracellular vesicle (EV) secretion is a highly conserved evolutionary trait in all organisms
in the three domains of life. The packaging and release of EVs appears to be a bulk-flow …

Simple Summary Small extracellular vesicles (sEVs) released by all cell types function as a
mediator in intercellular communication that can promote cell division and survival to …

Simple Summary Osteosarcoma (OS) is the most common bone tumor in the pediatric
population. Currently, no effective molecularly targeted therapies are available for OS. The …

Osteosarcoma (OS) is a skeletal tumor affecting mainly children and adolescents. The
presence of distance metastasis is frequent and it is localized preferentially to the lung …