Mesenchymal Stem Cell Therapy for Bone Repair of Human Hip Osteonecrosis with Bilateral Match-Control Evaluation: Impact of Tissue Source, Cell Count, Disease …

P Hernigou, Y Homma, J Hernigou… - Cells, 2024 - mdpi.com
We investigated the impact of mesenchymal stem cell (MSC) therapy on treating bilateral
human hip osteonecrosis, analyzing 908 cases. This study assesses factors such as tissue …

The Antagonism of neuropeptide Y type I receptor (Y1R) reserves the viability of bone marrow stromal cells in the milieu of osteonecrosis of femoral head (ONFH)

JY Ko, FS Wang, SH Chen, RW Wu, CC Hsu, SJ Kuo - Biomedicines, 2022 - mdpi.com
Neuropeptide Y (NPY)-Y1 receptor (Y1R) signaling is known to negatively affect bone
anabolism. Our study aimed at investigating the impact of NPY-Y1R signaling in the …

Runx2 overexpression promotes bone repair of osteonecrosis of the femoral head (ONFH)

HJ Xu, XZ Liu, L Yang, Y Ning, LL Xu, DM Sun… - Molecular Biology …, 2023 - Springer
Background Runt-related transcription factor-2 (Runx2) has been considered an inducer to
improve bone repair ability of mesenchymal stem cells (MSCs). Methods and results Twenty …