Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Psychoactive substances with chemical structures or pharmacological profiles that are
similar to traditional drugs of abuse continue to emerge on the recreational drug market …

Serotonin syndrome (SS)(also referred to as serotonin toxicity) is a potentially life-
threatening drug-induced toxidrome associated with increased serotonergic activity in both …

Unsuccessfully treated posttraumatic stress disorder (PTSD) is a serious and life-threatening
disorder. Two medications, paroxetine hydrochloride and sertraline hydrochloride, are …

Methylenedioxymethamphetamine (MDMA,'ecstasy') releases serotonin and
norepinephrine. MDMA is reported to produce empathogenic and prosocial feelings. It is …

Novel psychoactive substances are newly used designer drugs (" internet drugs"," research
chemicals"," legal highs") potentially posing similar health risks to classic illicit substances …

The pharmacology of novel psychoactive substances is mostly unknown. We evaluated the
transporter and receptor interaction profiles of a series of para-(4)-substituted amphetamines …

Abstract Rationale & objectives±3, 4-Methylenedioxymethamphetamine (MDMA) and
psilocybin are currently moving through the US Food and Drug Administration's phased drug …

3, 4-Methylenedioxymethamphetamine (MDMA; ecstasy) is being investigated in MDMA-
assisted psychotherapy. The present study characterized the safety pharmacology of single …

Acute hyponatremia can cause death if cerebral edema is not treated promptly. Conversely,
if chronic hyponatremia is corrected too rapidly, osmotic demyelination may ensue, which …