Immunotherapies inducing immunogenic cell death in cancer: insight of the innate immune system

KM Calvillo-Rodríguez, HY Lorenzo-Anota… - Frontiers in …, 2023 - frontiersin.org
Cancer immunotherapies include monoclonal antibodies, cytokines, oncolytic viruses,
cellular therapies, and other biological and synthetic immunomodulators. These are …

Loss of GABARAP mediates resistance to immunogenic chemotherapy in multiple myeloma

A Gulla, E Morelli, M Johnstone, M Turi, MK Samur… - Blood, 2024 - ashpublications.org
Immunogenic cell death (ICD) is a form of cell death by which cancer treatments can induce
a clinically relevant antitumor immune response in a broad range of cancers. In multiple …

DAMPening Tumor Immune Escape: The Role of Endoplasmic Reticulum Chaperones in Immunogenic Chemotherapy

S Cifric, M Turi, P Folino, C Clericuzio… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Preclinical and clinical research in the past two decades has redefined the
mechanism of action of some chemotherapeutics that are able to activate the immune …

Immunogenic cell stress and death sensitize tumors to immunotherapy

O Kepp, G Kroemer - Cells, 2023 - mdpi.com
The efficacy of chemotherapy with cytotoxicants and that of targeted therapies with more
sophisticated agents is limited due to the plasticity of malignant cells, which leads to the …

Cytotoxic Effects of the Combination of Pam3CSK4 with Carfilzomib, Ixazomib, and Venetoclax in Human Multiple Myeloma Cells

K Avci, MÖ Erdoğan, SH Yildiz, F Yavaşoğlu - Molecular Biology, 2024 - Springer
Proteasome inhibitors (PIs) are effective in the treatment of multiple myeloma (MM), which is
a plasma cell malignancy. Different options for treating MM are a subject of research …