Collagen is the most abundant structural protein found in humans and mammals, particularly
in the extracellular matrix (ECM). Its primary function is to hold the body together. The …

Collagen is an insoluble fibrous protein that composes the extracellular matrix in animals.
Although collagen has been used as a biomaterial since 1881, the properties and the …

Mesenchymal stem cells (MSCs), multipotent stromal cells, have attracted extensive
attention in the field of regenerative medicine and cell therapy due to the capacity of self …

Background. Abnormal endometrial repair after injury results in the formation of intrauterine
adhesions (IUA) and a thin endometrium, which are key causes for implantation failure and …

Protein-based biomaterials are becoming increasingly popular for biomedical applications
as they can replicate both chemical and mechanical properties of native tissues. Type I …

The field of regenerative medicine has recently seen an emerging trend toward
decellularized extracellular matrix (ECM) as a biological scaffold for stem cell-delivery …

Human Wharton's jelly stem cells (HWJSC) can be efficiently isolated from the umbilical
cord, and numerous reports have demonstrated that these cells can differentiate into several …

The activity of stem cell processes is regulated by internal and external signals of the cell
“niche”. In general, the niche of stem cells can be represented as the microenvironment of …

The concept of regenerating tissues, with properties and functions that mimic natural tissues,
has attracted significant attention in recent years. It provides potential solutions for many …

Pluripotent stem cells have the ability of self-renewal and pluripotency, which makes them
promising for application in cell therapy, tissue engineering and regenerative medicine …