Vibrational spectroscopy is an essential tool in chemical analyses, biological assays, and
studies of functional materials. Over the past decade, various coherent nonlinear vibrational …

Abstract “De novo” genes evolve from previously non-genic DNA. This strikes many of us as
remarkable, because it seems extraordinarily unlikely that random sequence would produce …

Abstract The coronavirus disease 2019 (COVID-19) is the latest biological hazard for the
novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though …

Ice-binding proteins (IBPs) from extremophile organisms can modulate ice formation and
growth. There are many (bio) technological applications of IBPs, from cryopreservation to …

Antifreeze glycoproteins (AFGPs) are produced by extremophiles to defend against tissue
damage in freezing climates. Cumbersome isolation from polar fish has limited probing …

Antifreeze glycoproteins (AFGPs) are a special kind of antifreeze proteins with strong
flexibility. Whether their antifreeze activity is achieved by reversibly or irreversibly binding to …

Background: De novo protein coding genes emerge from scratch in the non-coding regions
of the genome and have, per definition, no homology to other genes. Therefore, their …

Antifreeze glycoproteins (AFGPs) are able to bind to ice, halt its growth, and are the most
potent inhibitors of ice recrystallization known. The structural basis for AFGP's unique …

The molecular mechanism underlying inhibition of ice growth by polyproline (PPro), a
minimal antifreeze glycoprotein mimic, remains unclear. In this work, the change in the …

Cold-adapted organisms use antifreeze proteins (AFPs) or ice-nucleating proteins (INPs) for
the survival in freezing habitats. AFPs have been reported to be able to inhibit the activity of …