The influence of insulin-related genetic variants on fetal growth, fetal blood flow, and placental weight in a prospective pregnancy cohort

PK Reim, L Engelbrechtsen, D Gybel-Brask… - Scientific Reports, 2023 - nature.com
The fetal insulin hypothesis proposes that low birthweight and type 2 diabetes (T2D) in
adulthood may be two phenotypes of the same genotype. In this study we aimed to explore …

[HTML][HTML] Direct and INdirect effects analysis of Genetic lOci (DINGO): A software package to increase the power of locus discovery in GWAS meta-analyses of perinatal …

LD Hwang, G Cuellar-Partida, L Yengo, J Zeng… - medRxiv, 2023 - ncbi.nlm.nih.gov
Perinatal traits are influenced by genetic variants from both fetal and maternal genomes.
Genome-wide association studies (GWAS) of these phenotypes have typically involved …

[PDF][PDF] Analyse comparative et caractérisation des patrons pangénomiques de méthylation de l'ADN placentaire et de sang de cordon ombilical

M Groleau - 2023 - core.ac.uk
La méthylation de l'ADN est un mécanisme clé de régulation adaptative de l'expression des
gènes, laquelle est particulièrement dynamique dans les tissus embryonnaires. À cause de …