Intergenerational transmission of depression: clinical observations and molecular mechanisms

KM Sawyer, PA Zunszain, P Dazzan… - Molecular psychiatry, 2019 - nature.com
Maternal mental illness can have a devastating effect during the perinatal period, and has a
profound impact on the care that the baby receives and on the relationships that the baby …

Select early-life environmental exposures and DNA methylation in the placenta

M Mortillo, CJ Marsit - Current environmental health reports, 2023 - Springer
Abstract Purpose of Review To summarize recent literature relating early-life environmental
exposures on DNA methylation in the placenta, to identify how variation in placental …

Oxidative stress and inflammation mediate the effect of air pollution on cardio‐and cerebrovascular disease: a prospective study in nonsmokers

G Fiorito, J Vlaanderen, S Polidoro… - Environmental and …, 2018 - Wiley Online Library
Air pollution is associated with a broad range of adverse health effects, including mortality
and morbidity due to cardio‐and cerebrovascular diseases (CCVD), but the molecular …

Epigenetic alterations of maternal tobacco smoking during pregnancy: a narrative review

A Nakamura, O François, J Lepeule - International Journal of …, 2021 - mdpi.com
In utero exposure to maternal tobacco smoking is the leading cause of birth complications in
addition to being associated with later impairment in child's development. Epigenetic …

Mediation by placental DNA methylation of the association of prenatal maternal smoking and birth weight

A Cardenas, SM Lutz, TM Everson… - American Journal of …, 2019 - academic.oup.com
Prenatal maternal smoking is a risk factor for lower birth weight. We performed epigenome-
wide association analyses of placental DNA methylation (DNAm) at 720,077 cytosine …

Tobacco use during pregnancy

A Havard, JJ Chandran, JL Oei - Addiction, 2022 - Wiley Online Library
The use of tobacco during pregnancy is the leading preventable cause of pregnancy
complications and adverse birth outcomes. In high‐income countries, around one in 10 …

Epigenetics as a biomarker for early-life environmental exposure

R Schrott, A Song, C Ladd-Acosta - Current environmental health reports, 2022 - Springer
Abstract Purpose of Review There is interest in evaluating the developmental origins of
health and disease (DOHaD) which emphasizes the role of prenatal and early-life …

The genetics and epigenetics of neonatal abstinence syndrome

EM Wachman, LA Farrer - Seminars in Fetal and Neonatal Medicine, 2019 - Elsevier
Neonatal abstinence syndrome (NAS) due to in-utero opioid exposure is a growing
epidemic with significant variability in clinical presentation and severity. Currently, NAS …

Inflammation-related epigenetic risk and child and adolescent mental health: A prospective study from pregnancy to middle adolescence

ED Barker, CAM Cecil, E Walton… - Development and …, 2018 - cambridge.org
In 785 mother–child (50% male) pairs from a longitudinal epidemiological birth cohort, we
investigated associations between inflammation-related epigenetic polygenic risk scores (i …

Epigenetic variation in OPRM1 gene in opioid‐exposed mother‐infant dyads

EM Wachman, MJ Hayes, H Shrestha… - Genes, Brain and …, 2018 - Wiley Online Library
Neonatal abstinence syndrome (NAS) due to in‐utero opioid exposure has significant
variability of severity. Preliminary studies have suggested that epigenetic variation within the …