2023 Guideline for the management of patients with aneurysmal subarachnoid hemorrhage: a guideline from the American Heart Association/American Stroke …

BL Hoh, NU Ko, S Amin-Hanjani, SHY Chou… - Stroke, 2023 - Am Heart Assoc
Aim: The “2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid
Hemorrhage” replaces the 2012 “Guidelines for the Management of Aneurysmal …

Aneurysmal subarachnoid hemorrhage: review of the pathophysiology and management strategies

ML Osgood - Current neurology and neuroscience reports, 2021 - Springer
Abstract Purpose of Review Aneurysmal subarachnoid hemorrhage remains a devastating
disease process despite medical advances made over the past 3 decades. Much of the …

Early brain injury after poor-grade subarachnoid hemorrhage

V Rass, R Helbok - Current neurology and neuroscience reports, 2019 - Springer
Abstract Purpose of Review Over the last years, the focus of clinical and animal research in
subarachnoid hemorrhage (SAH) shifted towards the early phase after the bleeding based …

Systemic exosomal miR-193b-3p delivery attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage in mice

N Lai, D Wu, T Liang, P Pan, G Yuan, X Li, H Li… - Journal of …, 2020 - Springer
Background Inflammation is a potential crucial factor in the pathogenesis of subarachnoid
hemorrhage (SAH). Circulating microRNAs (miRNAs) are involved in the regulation of …

The critical care management of poor-grade subarachnoid haemorrhage

AL de Oliveira Manoel, A Goffi, TR Marotta… - Critical care, 2016 - Springer
Aneurysmal subarachnoid haemorrhage is a neurological syndrome with complex systemic
complications. The rupture of an intracranial aneurysm leads to the acute extravasation of …

Rethinking the initial changes in subarachnoid haemorrhage: focusing on real-time metabolism during early brain injury

Y Chen, I Galea, RL Macdonald, GKC Wong… - …, 2022 - thelancet.com
Over the last two decades, neurological researchers have uncovered many
pathophysiological mechanisms associated with subarachnoid haemorrhage (SAH), with …

Inhibition of AIM2 inflammasome activation alleviates GSDMD-induced pyroptosis in early brain injury after subarachnoid haemorrhage

B Yuan, X Zhou, Z You, W Xu, J Fan, S Chen… - Cell Death & …, 2020 - nature.com
Only a few types of inflammasomes have been described in central nervous system cells.
Among these, the absent in melanoma 2 (AIM2) inflammasome is primarily found in …

The pathophysiology of delayed cerebral ischemia

B Foreman - Journal of Clinical Neurophysiology, 2016 - journals.lww.com
Subarachnoid hemorrhage (SAH) affects 30,000 people in the Unites States alone each
year. Delayed cerebral ischemia occurs days after subarachnoid hemorrhage and …

Reduction of inflammation after administration of interleukin-1 receptor antagonist following aneurysmal subarachnoid hemorrhage: results of the Subcutaneous …

J Galea, K Ogungbenro, S Hulme, H Patel… - Journal of …, 2017 - thejns.org
OBJECTIVE Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating
cerebrovascular event with long-term morbidity and mortality. Patients who survive the initial …

Delayed cerebral ischemia after subarachnoid hemorrhage

A Ikram, MA Javaid, S Ortega-Gutierrez, M Selim… - Journal of Stroke and …, 2021 - Elsevier
Delayed cerebral ischemia (DCI) is the most feared complication of aneurysmal
subarachnoid hemorrhage (aSAH). It increases the mortality and morbidity associated with …