The severe acute respiratory syndrome coronavirus-2 emerged as a serious human
pathogen in late 2019, causing the disease coronavirus disease 2019 (COVID-19). The …

The clinical presentation of COVID‐19 due to infection with SARS‐CoV‐2 is highly variable
with the majority of patients having mild symptoms while others develop severe respiratory …

Adequate oxygen supply is essential for the human brain to meet its high energy demands.
Therefore, elaborate molecular and systemic mechanism are in place to enable adaptation …

Neurogenic hypertension is associated with excessive sympathetic nerve activity to the
kidneys and portions of the cardiovascular system. Here we examine the brain regions that …

Breathing is regulated automatically by neural circuits in the medulla to maintain
homeostasis, but breathing is also modified by behavior and emotion. Mice have rapid …

We examined cell type-specific expression and distribution of rat brain angiotensin-
converting enzyme 2 (ACE2), the receptor for SARS-CoV-2, in the rodent brain. ACE2 is …

Astroglia are neural cells, heterogeneous in form and function, which act as supportive
elements of the central nervous system; astrocytes contribute to all aspects of neural …

TASK2 (also known as KCNK5) channels generate pH-gated leak-type K+ currents to
control cellular electrical excitability,–. TASK2 is involved in the regulation of breathing by …

Respiratory chemoreceptor activity encoding arterial Pco2 and Po2 is a critical determinant
of ventilation. Currently, the relative importance of several putative chemoreceptor …

Inspiration is the inexorable active phase of breathing. The brainstem pre-Bötzinger complex
(preBötC) gives rise to inspiratory neural rhythm, but its underlying cellular and ionic bases …