Simple Summary Breast cancer remains the most common malignancy in women. In this
review, we explore the role of the CXCL12/CXCR4 pathway in breast cancer. We show that …

Autophagy, a cellular self-digestion process that is activated in response to stress, has a
functional role in tumor formation and progression. Cancer stem cells (CSCs) accounting for …

Background Contemporary deep learning approaches show cutting-edge performance in a
variety of complex prediction tasks. Nonetheless, the application of deep learning in …

Y-box binding protein 1 (YB-1) is a well-known oncogene highly expressed in various
cancers, including basal-like breast cancer (BLBC). Beyond its role as a transcription factor …

Invasive ductal carcinoma (IDC) is the most common histological subtype of malignant
breast cancer (BC), and accounts for 70–80% of all invasive BCs. IDC demonstrates great …

Objectives: keratin 16 (KRT16) is a type I cytokeratin that overexpressed in many kinds of
cancers, but unlike other keratins, KRT16 was poorly studied, so the aim of current study …

Background Cancer cells have developed molecular strategies to cope with evolutionary
stressors in the dynamic tumor microenvironment. Peroxisome proliferator-activated receptor …

Cancer drug response prediction is a crucial task in precision medicine, but existing models
have limitations in effectively representing molecular profiles of cancer cells. Specifically …

Keratins (KRTs) are the intermediate filament-forming proteins of epithelial cells, classified,
according to their physicochemical properties, into “soft” and “hard” keratins. They have a …

Cancer is a genetic disease which results in a functional imbalance between tumour-
repressive and oncogenic signals. The WHO highlights the burden of this indomitable …