Transition metal elements, such as copper, play diverse and pivotal roles in oncology. They
act as constituents of metalloenzymes involved in cellular metabolism, function as signaling …

Along with the wide use of pesticides in the world, the concerns over their health impacts are
rapidly growing. There is a huge body of evidence on the relation between exposure to …

Copper is an essential element in many biological processes. The critical functions
associated with copper have resulted from evolutionary harnessing of its potent redox …

Abstract Silicon dioxide nanoparticles (SiO2NPs) are widely applied in industry, chemical,
and cosmetics. SiO2NPs is known to induce pulmonary toxicity. In this study, we investigated …

Inflammation is a serious health issue worldwide that induces many diseases, such as
inflammatory bowel disease (IBD), sepsis, acute pancreatitis and lung injury. Thus, there is a …

Oxidative stress and endoplasmic reticulum (ER) stress are involved in different types of
stress-induced injuries. The aim of the present study was to evaluate the effect of Se …

The idea of “repurposing” of existing drugs provides an effective way to develop and identify
new therapies. Disulfiram (Antabuse), a drug commonly used for the treatment of alcoholism …

Many studies have shown that aflatoxin B1 (AFB1) can cause cytotoxicity in numerous cells
and organs induced by oxidative stress. However, the toxic effects and related mechanism of …

Abstract Paraquat (1, 1′-dimethyl-4, 4′-bipyridinium chloride; PQ) is widely and commonly
used as a herbicides in the world. PQ has been reported to be a major hazard because it …

Dithiocarbamates (DTC) are organosulfur compounds represented by a general structure
(R1R2) N-(C= S)-SX, where R can be substituted by an alkyl, alkylene, aryl, or similar other …