Tuberculosis (TB) is a severe infectious disease worldwide. The increasing emergence of
drug‐resistant Mycobacterium tuberculosis (Mtb) has markedly hampered TB control …

Mycobacterium tuberculosis possesses a dynamic cell envelope, which consists of a
peptidoglycan layer, a mycolic acid layer, and an arabinogalactan polysaccharide. This …

Herein a series of 4-aminoquinolines were synthesized in an attempt to optimize and study
the structural features related to LABIO-17 biological activity, a Mycobacterium tuberculosis …

Tuberculosis is an extremely serious problem of global public health. Its incidence is
worsened by the presence of multidrug-resistant (MDR) strains of Mycobacterium …

There is an unmet medical need for effective treatments against Mycobacterium abscessus
pulmonary infections, to which cystic fibrosis (CF) patients are particularly vulnerable …

The discovery of new antimicrobial agents as a means of treating drug-resistant microbial
pathogens is of utmost significance to overcome their immense risk to human well-being …

Isoniazid (INH) is one of the key molecules employed in the treatment of tuberculosis (TB),
the most deadly infectious disease worldwide. However, the efficacy of this cornerstone drug …

Mycobacterium tuberculosis (MTB) utilizes multiple mechanisms to obtain antibiotic
resistance during the treatment of infections. In addition, the biofilms, secreted by MTB, can …

Introduction Tuberculosis remains a significant concern in global public health due to its
intricate biology and propensity for developing antibiotic resistance. Discovering new drugs …

Tuberculosis has been a challenge to the world since prehistoric times, and with the advent
of drug-resistant strains, it has become more challenging to treat this infection. Ethionamide …