Abstract “Α picture is worth a thousand words.” This widely used adage sums up in a few
words the notion that a successful visual representation of a concept should enable easy …

PredictProtein is a meta-service for sequence analysis that has been predicting structural
and functional features of proteins since 1992. Queried with a protein sequence it returns …

Abstract Ocean Sampling Day was initiated by the EU-funded Micro B3 (Marine Microbial
Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine …

Background Transcriptomics, metabolomics, metagenomics, and other various next-
generation sequencing (-omics) fields are known for their production of large datasets …

Background Hierarchical clustering is an exploratory data analysis method that reveals the
groups (clusters) of similar objects. The result of the hierarchical clustering is a tree structure …

Abstract Background The Alternative Lengthening of Telomeres (ALT) pathway represents a
non-canonical mechanism of telomere maintenance that operates independently of the …

Nowadays CHK2 mutation is studied frequently in hereditary breast and ovarian cancer
patients in addition to BRCA1/BRCA2. CHK2 is a tumor suppressor gene that encodes a …

Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme involved in folate
metabolism and plays a central role in DNA methylation and biosynthesis. MTHFR mutations …

Methionine synthase encoded by the MTR gene is one of the key enzymes involved in the
SAM (S-Adenosyl Methionine) cycle catalyzing the conversion of homocysteine to …

Single nucleotide polymorphisms (SNPs) are the most common genetic polymorphisms and
play a major role in many inherited diseases. Methylenetetrahydrofolate dehydrogenase 1 …