Insights into antimicrobial and anti-inflammatory applications of plant bioactive compounds

G Mitropoulou, E Stavropoulou, N Vaou, Z Tsakris… - Microorganisms, 2023 - mdpi.com
Plants have long been thought to contribute to health promotion due to their fiber and
phenolic content, as well as their inherent biological potential. The bioactive derivatives of …

Complementary Approaches to Retinal Health Focusing on Diabetic Retinopathy

T Rák, A Kovács-Valasek, E Pöstyéni, A Csutak… - Cells, 2023 - mdpi.com
Diabetes mellitus affects carbohydrate homeostasis but also influences fat and protein
metabolism. Due to ophthalmic complications, it is a leading cause of blindness worldwide …

In silico bioprospecting of taraxerol as a main protease inhibitor of SARS-CoV-2 to develop therapy against COVID-19

S Mujwar, RK Harwansh - Structural Chemistry, 2022 - Springer
COVID-19 was caused by a novel coronavirus known as SARS-CoV-2. The COVID-19
disease outbreak has been avowed as a global pandemic by the World Health Organization …

Antioxidant and Antihyperglycemic Effects of Ephedra foeminea Aqueous Extract in Streptozotocin-Induced Diabetic Rats

MNA Hajleh, KM Khleifat, M Alqaraleh, E Al-Hraishat… - Nutrients, 2022 - mdpi.com
Background: Ephedra foeminea is known in Jordan as Alanda and traditionally. It is used to
treat respiratory symptoms such as asthma and skin rashes as an infusion in boiling water …

Antidiabetic Actions of Ethanol Extract of Camellia Sinensis Leaf Ameliorates Insulin Secretion, Inhibits the DPP-IV Enzyme, Improves Glucose Tolerance, and …

P Ansari, JMA Hannan, ST Choudhury, SS Islam… - Medicines, 2022 - mdpi.com
Camellia sinensis (green tea) is used in traditional medicine to treat a wide range of
ailments. In the present study, the insulin-releasing and glucose-lowering effects of the …

Phloretamide Prevent Hepatic and Pancreatic Damage in Diabetic Male Rats by Modulating Nrf2 and NF-κB

R Al-Hussan, NA Albadr, GM Alshammari, SA Almasri… - Nutrients, 2023 - mdpi.com
This study examined the effect of phloretamide, a metabolite of phloretin, on liver damage
and steatosis in streptozotocin-induced diabetes mellitus (DM) in rats. Adult male rats were …

Expression Profiling of Pdx1, Ngn3, and MafA in the Liver and Pancreas of Recovering Streptozotocin-Induced Diabetic Rats

AM Al-Adsani, AN Al-Otaibi, SA Barhoush… - Genes, 2022 - mdpi.com
Studies in animal diabetic models have demonstrated the possibility of islet regeneration
through treatment with natural extracts, such as Allium sativum (garlic). This study aimed to …

[HTML][HTML] Pancreatic beta cell regenerative potential of Zanthoxylum chalybeum Engl. Aqueous stem bark extract

CN Kimani, H Reuter, SH Kotzé, P Venter… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Zanthoxylum chalybeum Engl. is endemic to
Africa and has been used traditionally to treat diabetes mellitus. Moreover, its …

Gymnemic acid ameliorates pancreatic β-cell dysfunction by modulating Pdx1 expression: a possible strategy for β-cell regeneration

P Kannan, M Raghunathan, T Mohan… - Tissue Engineering and …, 2022 - Springer
Background: Endogenous pancreatic β-cell regeneration is a promising therapeutic
approach for enhancing β-cell function and neogenesis in diabetes. Various findings have …

Computational Design of Plant‐Based Antistress Agents Targeting Nociceptin Receptor

V Sharma, S Mujwar, D Sharma, R Das… - Chemistry & …, 2023 - Wiley Online Library
Stress is the body's reaction to the challenges it faces, and it produces a multitude of
chemical molecules known as stressors as a result of these reactions. It's also a …