Update on diagnosis, pathophysiology, and management of diabetic kidney disease

M Sugahara, WLW Pak, T Tanaka, SCW Tang… - …, 2021 - Wiley Online Library
Diabetic kidney disease (DKD) is a chronic complication of diabetes mellitus which may
eventually lead to end‐stage kidney disease (ESKD). Despite improvements in glycaemic …

The role of renal hypoxia in the pathogenesis of diabetic kidney disease: a promising target for newer renoprotective agents including SGLT2 inhibitors?

AC Hesp, JA Schaub, PV Prasad, V Vallon… - Kidney international, 2020 - Elsevier
Diabetic kidney disease is the most common cause of end-stage kidney disease and poses
a major global health problem. Finding new, safe, and effective strategies to halt this disease …

[HTML][HTML] The role of oxidative stress and hypoxia in renal disease

T Honda, Y Hirakawa, M Nangaku - Kidney research and clinical …, 2019 - ncbi.nlm.nih.gov
Oxygen is required to sustain aerobic organisms. Reactive oxygen species (ROS) are
constantly released during mitochondrial oxygen consumption for energy production. Any …

Recent advances in medical image processing for the evaluation of chronic kidney disease

I Alnazer, P Bourdon, T Urruty, O Falou, M Khalil… - Medical Image …, 2021 - Elsevier
Assessment of renal function and structure accurately remains essential in the diagnosis
and prognosis of Chronic Kidney Disease (CKD). Advanced imaging, including Magnetic …

Targeting inflammation for the treatment of Diabetic Kidney Disease: A five-compartment mechanistic model

A Hofherr, J Williams, LM Gan, M Söderberg… - BMC nephrology, 2022 - Springer
Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide. Mortality
and morbidity associated with DKD are increasing with the global prevalence of type 2 …

Role of oxidative stress in diabetes-induced complications and their management with antioxidants

H Singh, R Singh, A Singh, H Singh… - … of Physiology and …, 2023 - Taylor & Francis
Diabetes mellitus (DM) is a huge global health issue and one of the most studied diseases,
with a large global prevalence. Oxidative stress is a cytotoxic consequence of the excessive …

[HTML][HTML] Magnetic resonance imaging to evaluate kidney structure, function, and pathology: Moving toward clinical application

ST Francis, NM Selby, MW Taal - American Journal of Kidney Diseases, 2023 - Elsevier
Recent advances in multiparametric magnetic resonance imaging (MRI) allow multiple
quantitative measures to assess kidney morphology, tissue microstructure, oxygenation …

Hypoxia-inducible factors and diabetic kidney disease—How deep can we go?

AM Stanigut, C Pana, M Enciu, M Deacu… - International Journal of …, 2022 - mdpi.com
Diabetes is one of the leading causes of chronic kidney disease (CKD), and multiple
underlying mechanisms involved in pathogenesis of diabetic nephropathy (DN) have been …

Diffusion-magnetic resonance imaging predicts decline of kidney function in chronic kidney disease and in patients with a kidney allograft

L Berchtold, LA Crowe, C Combescure, M Kassaï… - Kidney International, 2022 - Elsevier
Kidney cortical interstitial fibrosis is highly predictive of kidney prognosis and is currently
assessed by evaluation of a biopsy. Diffusion-weighted magnetic resonance imaging is a …

Future of kidney imaging: functional magnetic resonance imaging and kidney disease progression

S Copur, F Yavuz, AA Sag, KR Tuttle… - European journal of …, 2022 - Wiley Online Library
Introduction Chronic kidney disease (CKD) which is a common cause of death has an
increasing trend, but there is no established approach for predicting CKD progression yet …