Ethnic disparities in childhood leukemia survival by border residence: a Texas population‐based analysis
MI Castellanos, AO Oluyomi, TM Chambers… - Cancer, 2023 - Wiley Online Library
Abstract Background The US–Mexico border is a medically underserved region where
survival disparities have been observed in adults diagnosed and treated for various …
survival disparities have been observed in adults diagnosed and treated for various …
Novel and replicated clinical and genetic risk factors for toxicity from high‐dose methotrexate in pediatric acute lymphoblastic leukemia
M Zobeck, MB Bernhardt, KY Kamdar… - … : The Journal of …, 2023 - Wiley Online Library
Abstract Study Objective Methotrexate (MTX) is a key component of treatment for high‐risk
pediatric acute lymphoblastic leukemia (ALL) but may cause acute kidney injury and …
pediatric acute lymphoblastic leukemia (ALL) but may cause acute kidney injury and …
HyperCVAD versus pegaspargase‐containing regimens for Hispanic adults with newly diagnosed B‐cell acute lymphoblastic leukemia
BJ Lee, SP Griffin, J Doh, A Chan… - European Journal of …, 2024 - Wiley Online Library
Objective There are significant disparities in outcomes among Hispanic patients with acute
lymphoblastic leukemia (ALL). Recent studies have demonstrated favorable outcomes of …
lymphoblastic leukemia (ALL). Recent studies have demonstrated favorable outcomes of …
Toxicity associated with high-dose intravenous methotrexate for hematological malignancies
J Wight, M Ku, M Garwood, D Carradice… - Leukemia & …, 2022 - Taylor & Francis
Intravenous high-dose methotrexate (HD-MTX) is a critical chemotherapeutic agent in
hematological malignancies, however, data are lacking on how to predict and prevent …
hematological malignancies, however, data are lacking on how to predict and prevent …
Ethnic‐specific predictors of neurotoxicity among patients with pediatric acute lymphoblastic leukemia after high‐dose methotrexate
RD Harris, MB Bernhardt, MC Zobeck, OA Taylor… - Cancer, 2023 - Wiley Online Library
Background High‐dose methotrexate (HD‐MTX; 5000 mg/m2) is an important component of
curative therapy in many treatment regimens for high‐risk pediatric acute lymphoblastic …
curative therapy in many treatment regimens for high‐risk pediatric acute lymphoblastic …
Increased incidence of Pegaspargase-induced hypertriglyceridemia and associated pancreatitis observed in the Hispanic adult patient population
BJ Lee, J Doh, A Chan, D Jeyakumar… - Leukemia & …, 2022 - Taylor & Francis
Pegaspargase (PEG) is a long-acting formulation of L-asparaginase (L-ASP) that induces
cell apoptosis via exogenous depletion of asparagine, a necessary amino acid for synthesis …
cell apoptosis via exogenous depletion of asparagine, a necessary amino acid for synthesis …
A modified CALGB 10403 in adolescents and young adults with acute lymphoblastic leukemia in Central America
J Rangel-Patiño, YL Lee-Tsai… - Blood …, 2023 - ashpublications.org
Abstract Mexico and Central America have a high incidence of acute lymphoblastic
leukemia (ALL) in adolescents and young adults. Historically, this patient group has been …
leukemia (ALL) in adolescents and young adults. Historically, this patient group has been …