The computational and neural basis of voluntary motor control and planning

SH Scott - Trends in cognitive sciences, 2012 - cell.com
Optimal feedback control (OFC) provides a powerful tool to interpret voluntary motor control,
highlighting the importance of sensory feedback in the control and planning of movement …

Inconvenient truths about neural processing in primary motor cortex

SH Scott - The Journal of physiology, 2008 - Wiley Online Library
Primary motor cortex (MI) plays an important role in voluntary motor behaviour, yet
considerable debate remains on how neural processing within this brain region contributes …

[图书][B] Synergy

ML Latash - 2008 - books.google.com
Synergy discusses a general problem in biology: The lack of an adequate language for
formulating biologically specific problems. Written for an inquisitive reader who is not …

[HTML][HTML] Preference distributions of primary motor cortex neurons reflect control solutions optimized for limb biomechanics

TP Lillicrap, SH Scott - Neuron, 2013 - cell.com
Neurons in monkey primary motor cortex (M1) tend to be most active for certain directions of
hand movement and joint-torque loads applied to the limb. The origin and function of these …

[HTML][HTML] Stroke rehabilitation reaches a threshold

CE Han, MA Arbib, N Schweighofer - PLoS computational biology, 2008 - journals.plos.org
Motor training with the upper limb affected by stroke partially reverses the loss of cortical
representation after lesion and has been proposed to increase spontaneous arm use …

[HTML][HTML] Distributed task-specific processing of somatosensory feedback for voluntary motor control

M Omrani, CD Murnaghan, JA Pruszynski, SH Scott - Elife, 2016 - elifesciences.org
Corrective responses to limb disturbances are surprisingly complex, but the neural basis of
these goal-directed responses is poorly understood. Here we show that somatosensory …

[HTML][HTML] Using a compound gain field to compute a reach plan

SWC Chang, C Papadimitriou, LH Snyder - Neuron, 2009 - cell.com
A gain field, the scaling of a tuned neuronal response by a postural signal, may help support
neuronal computation. Here, we characterize eye and hand position gain fields in the …

Goal-dependent modulation of fast feedback responses in primary motor cortex

JA Pruszynski, M Omrani, SH Scott - Journal of Neuroscience, 2014 - Soc Neuroscience
Many human studies have demonstrated that rapid motor responses (ie, muscle-stretch
reflexes) to mechanical perturbations can be modified by a participant's intended response …

How does the brain solve muscle redundancy? Filling the gap between optimization and muscle synergy hypotheses

M Hirashima, T Oya - Neuroscience research, 2016 - Elsevier
The question of how the central nervous system coordinates redundant muscles has been a
long-standing problem in motor neuroscience. The optimization hypothesis posits that the …

Descending systems translate transient cortical commands into a sustained muscle activation signal

U Shalit, N Zinger, M Joshua, Y Prut - Cerebral cortex, 2012 - academic.oup.com
Controlling motor actions requires online adjustments of time-varying parameters. Although
numerous studies have attempted to identify the parameters coded in different motor sites …