Obesity paradox in advanced kidney disease: from bedside to the bench

N Naderi, CE Kleine, C Park, JT Hsiung… - Progress in …, 2018 - Elsevier
While obesity is associated with a variety of complications including diabetes, hypertension,
cardiovascular disease and premature death, observational studies have also found that …

C-reactive protein: An inflammatory marker with specific role in physiology, pathology, and diagnosis

S Chandrashekara - Internet Journal of Rheumatology and …, 2014 - chanrejournals.com
C-reactive protein (CRP), an acute phase protein belonging to pentraxin family of proteins,
increases 1000-fold or more in concentration in blood during the occurrence of an injury …

Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosis

RC Shroff, R McNair, N Figg, JN Skepper, L Schurgers… - Circulation, 2008 - Am Heart Assoc
Background—Vascular calcification is associated with increased morbidity and mortality in
stage V chronic kidney disease, yet its early pathogenesis and initiating mechanisms in vivo …

Chronic mineral dysregulation promotes vascular smooth muscle cell adaptation and extracellular matrix calcification

RC Shroff, R McNair, JN Skepper, N Figg… - Journal of the …, 2010 - journals.lww.com
In chronic kidney disease (CKD) vascular calcification occurs in response to deranged
calcium and phosphate metabolism and is characterized by vascular smooth muscle cell …

Chronic kidney disease and clinical outcome in patients with acute stroke

G Yahalom, R Schwartz, Y Schwammenthal… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—Chronic kidney disease (CKD) is increasingly recognized as an
independent risk factor for cardiovascular disease and stroke. Our aim was to examine the …

[HTML][HTML] Exploring the biology of vascular calcification in chronic kidney disease: what's circulating?

M Schoppet, RC Shroff, LC Hofbauer, CM Shanahan - Kidney international, 2008 - Elsevier
Chronic kidney disease (CKD) is associated with fatal cardiovascular consequences in part
due to ectopic calcification of soft tissues particularly arteries, capillaries, and cardiac valves …

[HTML][HTML] Role of C-reactive protein in kidney diseases

J Li, J Chen, H Lan, Y Tang - Kidney Diseases, 2023 - karger.com
Background: C-reactive protein (CRP) is an acute-phase protein and has been found to be a
risk factor for acute kidney injury (AKI) and chronic kidney diseases (CKD). However, the …

The impact of insulin resistance and chronic kidney disease on inflammation and cardiovascular disease

CE Kosmas, D Silverio, C Tsomidou… - Clinical Medicine …, 2018 - journals.sagepub.com
There is extensive evidence showing that insulin resistance (IR) is associated with chronic
low-grade inflammation. Furthermore, IR has been shown to increase the risk for …

Mechanisms for increased cardiovascular disease in chronic kidney dysfunction

S Yamamoto, V Kon - Current opinion in nephrology and …, 2009 - journals.lww.com
The mechanisms underlying the heightened risk for CVD in CKD have been the focus of
intense study and may relate to the combined effects of traditional and CKD-specific risks …

Intact fibroblast growth factor 23 levels predict incident cardiovascular event before but not after the start of dialysis

C Nakano, T Hamano, N Fujii, Y Obi, I Matsui… - Bone, 2012 - Elsevier
PURPOSE: Low 25-hydroxyvitamin D (25D), increased levels of fibroblast growth factor 23
(FGF23), parathyroid hormone (PTH), and alkaline phosphatase (ALP) were reported to be …