The genome editing revolution
AM Khalil - Journal of genetic engineering and biotechnology, 2020 - Elsevier
Background Development of efficient strategies has always been one of the great
perspectives for biotechnologists. During the last decade, genome editing of different …
perspectives for biotechnologists. During the last decade, genome editing of different …
[HTML][HTML] Genome editing: A perspective on the application of CRISPR/Cas9 to study human diseases
DR Rodríguez‑Rodríguez… - International …, 2019 - spandidos-publications.com
Genome editing reemerged in 2012 with the development of CRISPR/Cas9 technology,
which is a genetic manipulation tool derived from the defense system of certain bacteria …
which is a genetic manipulation tool derived from the defense system of certain bacteria …
Clinical applications of CRISPR‐based genome editing and diagnostics
Clustered regularly interspaced short palindromic repeats (CRISPR)‐driven genome editing
has rapidly transformed preclinical biomedical research by eliminating the underlying …
has rapidly transformed preclinical biomedical research by eliminating the underlying …
[HTML][HTML] An update on the application of CRISPR technology in clinical practice
F Morshedzadeh, M Ghanei, M Lotfi, M Ghasemi… - Molecular …, 2024 - Springer
The CRISPR/Cas system, an innovative gene-editing tool, is emerging as a promising
technique for genome modifications. This straightforward technique was created based on …
technique for genome modifications. This straightforward technique was created based on …
[HTML][HTML] CRISPR/Cas9: the Jedi against the dark empire of diseases
Abstract Advances in Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR
associated system (CRISPR/Cas9) has dramatically reshaped our ability to edit genomes …
associated system (CRISPR/Cas9) has dramatically reshaped our ability to edit genomes …
[HTML][HTML] Novel genetic therapeutic approaches for modulating the severity of β‑thalassemia
F Amjad, T Fatima, T Fayyaz… - Biomedical …, 2020 - spandidos-publications.com
Thalassemia is a genetic haematological disorder that arises due to defects in the α and β‑
globin genes. Worldwide, 0.3‑0.4 million children are born with haemoglobinopathies per …
globin genes. Worldwide, 0.3‑0.4 million children are born with haemoglobinopathies per …
Exosomes for CRISPR-Cas9 delivery: the cutting edge in genome editing
Gene mutation correction was challenging until the discovery of clustered regularly
interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein (Cas) …
interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein (Cas) …
[HTML][HTML] CRISPR-cas gene-editing as plausible treatment of neuromuscular and nucleotide-repeat-expansion diseases: A systematic review
Introduction The system of clustered regularly interspaced short palindromic repeats
(CRISPR) and CRISPR-associated proteins (cas) is a new technology that allows easier …
(CRISPR) and CRISPR-associated proteins (cas) is a new technology that allows easier …
Machine learning meets cancer
EV Varlamova, MA Butakova, VV Semyonova… - Cancers, 2024 - mdpi.com
Simple Summary This review examines the latest technologies using machine learning (ML)
methods, including the use of convolutional neural networks, decision trees, and generative …
methods, including the use of convolutional neural networks, decision trees, and generative …
[HTML][HTML] The CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia
I García-Tuñón, M Hernández-Sánchez, JL Ordoñez… - Oncotarget, 2017 - ncbi.nlm.nih.gov
CRISPR/Cas9 technology was used to abrogate p210 oncoprotein expression in the Boff-
p210 cell line, a pro-B line derived from interlukin-3-dependent Baf/3, that shows IL-3 …
p210 cell line, a pro-B line derived from interlukin-3-dependent Baf/3, that shows IL-3 …