The proteasome is a well-identified therapeutic target for cancer treatment. It acts as the
main protein degradation system in the cell and degrades key mediators of cell growth …

The complexity of breast cancer includes many interacting biological processes that make it
difficult to find appropriate therapeutic treatments. Therefore, identifying potential diagnostic …

Proteasome a highly sophisticated systems that alter protein structure and function.
Proteasome 26S Subunit, Non-ATPase (PSMD) genes have been implicated in several …

Aims PSMD family members, as important components of the 26S proteasome, are well
known to be involved in protein degradation. However, their role in glioblastoma (GBM) has …

Ever since the ubiquitin proteasome system was characterized, efforts have been made to
manipulate its function to abrogate the progression of cancer. As a result, the anti-cancer …

Background The 26S proteasome non-ATPase regulatory subunit 11 is a multiprotein
complex involved in the ATP-dependent degradation of ubiquitinated proteins, and PSMD11 …

Background: Although previous studies reported that 26S proteasome non-ATPase
regulatory subunit 2 (PSMD2) is involved in many human cancers. However, its clinical …

The proteasome has been validated as an anticancer drug target, while the role of a subunit
of proteasome, PSMC6, in lung adenocarcinoma (LUAD) has not been fully unveiled. In this …

Proteasome 26S subunit, non-ATPase 12 (PSMD12) genes have been implicated in several
types of malignancies but the role of PSMD12 in pancreatic cancer (PC) remains elusive …

The digestive tract, particularly the intestine, represents one of the main sites of interactions
with the environment, playing the gut mucosa a crucial role in the digestion and absorption …