Artificial intelligence in assisting pathogenic microorganism diagnosis and treatment: a review of infectious skin diseases
R Han, X Fan, S Ren, X Niu - Frontiers in Microbiology, 2024 - frontiersin.org
The skin, the largest organ of the human body, covers the body surface and serves as a
crucial barrier for maintaining internal environmental stability. Various microorganisms such …
crucial barrier for maintaining internal environmental stability. Various microorganisms such …
Tackling the Antimicrobial Resistance “Pandemic” with Machine Learning Tools: A Summary of Available Evidence
Antimicrobial resistance is recognised as one of the top threats healthcare is bound to face
in the future. There have been various attempts to preserve the efficacy of existing …
in the future. There have been various attempts to preserve the efficacy of existing …
Web Service for HIV Drug Resistance Prediction Based on Analysis of Amino Acid Substitutions in Main Drug Targets
AI Paremskaia, AV Rudik, DA Filimonov, AA Lagunin… - Viruses, 2023 - mdpi.com
Predicting viral drug resistance is a significant medical concern. The importance of this
problem stimulates the continuous development of experimental and new computational …
problem stimulates the continuous development of experimental and new computational …
[HTML][HTML] Quantitative Prediction of Human Immunodeficiency Virus Drug Resistance
EA Stolbova, LA Stolbov, DA Filimonov, VV Poroikov… - Viruses, 2024 - mdpi.com
Drug resistance of pathogens, including viruses, is one of the reasons for decreased efficacy
of therapy. Considering the impact of HIV type 1 (HIV-1) on the development of progressive …
of therapy. Considering the impact of HIV type 1 (HIV-1) on the development of progressive …
Developing Dynamic Structure‐Based Pharmacophore and ML‐Trained QSAR Models for the Discovery of Novel Resistance‐Free RET Tyrosine Kinase Inhibitors …
Activation of RET tyrosine kinase plays a critical role in the pathogenesis of various cancers,
including non‐small cell lung cancer, papillary thyroid cancers, multiple endocrine …
including non‐small cell lung cancer, papillary thyroid cancers, multiple endocrine …
Improving Predictive Efficacy for Drug Resistance in Novel HIV-1 Protease Inhibitors through Transfer Learning Mechanisms
The human immunodeficiency virus presents a significant global health challenge due to its
rapid mutation and the development of resistance mechanisms against antiretroviral drugs …
rapid mutation and the development of resistance mechanisms against antiretroviral drugs …
Natural Polymorphisms D60E and I62V Stabilize a Closed Conformation in HIV-1 Protease in the Absence of an Inhibitor or Substrate
TT Tran, GE Fanucci - Viruses, 2024 - mdpi.com
HIV infection remains a global health issue plagued by drug resistance and virological
failure. Natural polymorphisms (NPs) contained within several African and Brazilian …
failure. Natural polymorphisms (NPs) contained within several African and Brazilian …
Multi-Drug Artificial Neural Network Models for Predicting HIV-1 RTI Resistance
Drug resistance is a major barrier to effectively treating HIV/AIDS, necessitating the
exploration of novel drugs and an understanding of resistance mechanisms. Genotypic and …
exploration of novel drugs and an understanding of resistance mechanisms. Genotypic and …