Duchenne muscular dystrophy is a severe, progressive, muscle-wasting disease that leads
to difficulties with movement and, eventually, to the need for assisted ventilation and …

Nrf2 and its endogenous inhibitor, Keap1, function as a ubiquitous, evolutionarily conserved
intracellular defense mechanism to counteract oxidative stress. Sequestered by cytoplasmic …

Nothing is known about the potential implication of gut microbiota in skeletal muscle
disorders. Here, we provide evidence that fecal microbiota composition along with …

Beside inherited muscle diseases many catabolic conditions such as insulin resistance,
malnutrition, cancer growth, aging, infections, chronic inflammatory status, inactivity, obesity …

Duchenne muscular dystrophy (DMD) is characterized by rapid wasting of skeletal muscle.
Mitochondrial dysfunction is a well-known pathological feature of DMD. However, whether …

Mitochondrial stress may be a secondary contributor to muscle weakness in inherited
muscular dystrophies. Duchenne muscular dystrophy has received the majority of attention …

Abstract Duchenne Muscular Dystrophy (DMD) is a fatal neuromuscular disease that is
characterised by dystrophin-deficiency and chronic Ca 2+-induced skeletal muscle wasting …

Several molecular mechanisms are involved in the regulation of skeletal muscle function.
Among them, mitochondrial activity can be identified. The mitochondria is an important and …

Background and Purpose Duchenne muscular dystrophy (DMD), caused by dystrophin
deficiency, results in chronic inflammation and irreversible skeletal muscle degeneration …

Thyroid hormone (TH) and autophagy share similar functions in regulating skeletal muscle
growth, regeneration, and differentiation. Although TH recently has been shown to increase …