Genetics of cholesterol-related genes in metabolic syndrome: a review of current evidence

SK Wong, FF Ramli, A Ali, NI Ibrahim - Biomedicines, 2022 - mdpi.com
Metabolic syndrome (MetS) refers to a cluster of metabolic dysregulations, which include
insulin resistance, obesity, atherogenic dyslipidemia and hypertension. The complex …

Association of interleukin-6 polymorphisms with obesity: A systematic review and meta-analysis

M Gholami, F Sharifi, S Shahriari, K Khoshnevisan… - Cytokine, 2019 - Elsevier
Obesity is a common metabolic disorder with increasing trend all around the world. Owing to
the role of pro-inflammatory cytokines on obesity, we aimed to investigate the role of …

Genetic association of ADIPOQ gene variants (-3971A>G and +276G>T) with obesity and metabolic syndrome in North Indian Punjabi population

H Kaur, B Badaruddoza, V Bains, A Kaur - PloS one, 2018 - journals.plos.org
Background and aims At present obesity and metabolic syndrome (MetS) in India are the
most challenging health problems. It is also well accepted that obesity is a significant risk …

Rare Variants of Obesity-Associated Genes in Young Adults with Abdominal Obesity

A Bairqdar, E Shakhtshneider, D Ivanoshchuk… - Journal of Personalized …, 2023 - mdpi.com
The increase in the prevalence of overweight, obesity and associated diseases is a serious
problem. The aim of the study was to identify rare variants in obesity-associated genes in …

Association of ADIPOQ Single-Nucleotide Polymorphisms with the Two Clinical Phenotypes Type 2 Diabetes Mellitus and Metabolic Syndrome in a Kinh Vietnamese …

S Truong, NQ Tran, PT Ma, CK Hoang… - … syndrome and obesity …, 2022 - Taylor & Francis
Purpose Genetic factors play an important role in the development of type 2 diabetes
mellitus (T2DM) and metabolic syndrome (MetS). However, few genetic association studies …

Serum adiponectin and cortisol levels are not affected by studied ADIPOQ gene variants: Tehran lipid and glucose study

M Nezhadali, SA Mesbah-Namin, M Hedayati… - BMC Endocrine …, 2022 - Springer
Background Obesity is a major public health concern in developed and even developing
countries worldwide. Adiponectin is a protein secreted by adipose tissue that modulates …

Risk variants of obesity associated genes demonstrate BMI raising effect in a large cohort

M Saqlain, M Khalid, M Fiaz, S Saeed… - Plos one, 2022 - journals.plos.org
Obesity is highly polygenic disease where several genetic variants have been reportedly
associated with obesity in different ethnicities of the world. In the current study, we identified …

Impact of inflammatory cytokine and adipokine gene variations in the development of HIV‐associated lipodystrophy

G Namdev, R Choudhari, Shyamveer… - The Journal of Gene …, 2023 - Wiley Online Library
Cytokines affect lipid and glucose metabolism and also alter the body's habitus. They play a
role in the development of lipodystrophy syndrome. Adipocytes secrete the pro‐inflammatory …

Adiponectin Gene Polymorphisms and Possible Susceptibility to Metabolic Syndrome among the Sudanese Population: A Case‐Control Study

AS Mosad, GA Elfadil, A Gassoum… - International Journal …, 2023 - Wiley Online Library
Background and Aim. The adiponectin gene (ADIPQ) has been identified as a human
adiposity marker of metabolic syndrome (MetS) in several ethnic cultures. This study aimed …

[HTML][HTML] Association of ADIPOQ Single Nucleotide Polymorphisms (SNPs) with Obesity Risk in Different Populations: A Systematic Review and Analysis

N Sikhayeva, A Nursafina, A Satayeva… - Iranian Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Thirty-two single nucleotide polymorphisms (SNPs) are commonly found in
ADIPOQ. APN levels are decreased in obesity, and SNPs of the ADIPOQ gene affecting APN …