The kinase-inducible domain interacting (KIX) domain is a highly conserved independently
folding three-helix bundle that serves as a docking site for transcription factors, whereupon …

Basic transcriptional machinery in eukaryotes is assisted by a number of cofactors, which
either increase or decrease the rate of transcription. Mediator complex is one such cofactor …

The Mediator complex is known to be a master coordinator of transcription by RNA
polymerase II, and this complex is recruited by transcription factors (TF s) to target promoters …

Upon pathogen infection, plants undergo dramatic transcriptome reprogramming to shift
from normal growth and development to immune response. During this rapid process, the …

Plant adjustment to environmental changes involves complex crosstalk between extrinsic
and intrinsic cues. In the past two decades, extensive research has elucidated the key roles …

Eukaryotic cells are complex biological systems that depend on highly connected molecular
interaction networks with intrinsically disordered proteins as essential components. Through …

Understanding of mechanistic details of Mediator functioning in plants is impeded as the
knowledge of subunit organization and structure is lacking. In this study, an interaction map …

Mediator, a multisubunit protein complex, is a signal processor that conveys regulatory
information from transcription factors to RNA polymerase II and therefore plays an important …

Increasing temperatures impact plant biochemistry, but the effects can be highly variable.
Both external and internal factors modulate how plants respond to rising temperatures. One …

Root hairs are epidermal cell extensions that increase the root surface for water and nutrient
acquisition. Thus, both the initiation and elongation of root hairs are critical for soil …