Although reactive oxygen species (ROS) are essential for cellular processes, excessive
ROS could be a major cause of various inflammatory diseases because of the oxidation of …

Hydrogen peroxide emerged as major redox metabolite operative in redox sensing,
signaling and redox regulation. Generation, transport and capture of H 2 O 2 in biological …

In radiation therapy for cancer, the therapeutic ratio represents an optimal balance between
tumor control and normal tissue complications. As improvements in the therapeutic arsenal …

Reactive oxygen species, such as superoxide and hydrogen peroxide, are generated in all
cells by mitochondrial and enzymatic sources. Left unchecked, these reactive species can …

Oxidative stress is considered a major contributor to etiology of both “normal” senescence
and severe pathologies with serious public health implications. Mitochondria generate …

Free radicals are reactive compounds that are naturally produced in the human body. They
can exert positive effects (eg on the immune system) or negative effects (eg lipids, proteins …

Oxidative stress is characterized by imbalanced reactive oxygen species (ROS) production
and antioxidant defenses. Two main antioxidant systems exist. The nonenzymatic system …

The increase in the formation of reactive oxygen and reactive nitrogen species of
endogenous or exogenous origin causes oxidative stress due to pro-oxidant and antioxidant …

Since the discovery of catalase, it has been postulated that aerobic organisms generate
enough oxidants to threaten their own fitness and, in particular, their genetic stability. An …

In recent years, antibiotic pollution has become worse, especially in China. In this study, the
ecotoxicological effects of four frequently used antibiotics with different lipophilic degrees …