The diversity of molecular entities emerging from a single gene are recognized. Several
studies have thus established the cellular role (s) of transcript variants and protein isoforms …

Guanine‐rich oligonucleotides existing in both DNA and RNA are able to fold into four‐
stranded DNA secondary structures via Hoogsteen type hydrogen‐bonding, where four …

Background Calcimycin (A23187) is a polyether antibiotic and divalent cation ionophore,
extracted from Streptomyces chartrecensis. With wide variety of antimicrobial activities, it …

The TFE3 fusion gene, byproduct of Xp11. 2 translocation, is the diagnostic marker for
translocation renal cell carcinoma (tRCC). Absence of any clinically recognized therapy for …

As a prescribed antioxidant, N-Acetylcysteine is used in treating disease and supportive
care. However, N-acetylcysteine's role in cancer therapy is controversial and needs to be …

Currently, G-quadruplex structure targeting strategies are considered as a promising
anticancer approach. The purpose of this research is to expand the options for G-quadruplex …

Renal cell carcinoma remains one of the most common malignant tumors and is associated
with significant challenges in drug therapy. Zinc has been reported to be of pharmacological …

Abstract G-Quadruplexes (G4Q) are higher-order, four-stranded structures that can be
formed by repeated guanine tracts in human genomes. In this study, we used a structure …

Calcimycin (A23187) is a polyether antibiotic and divalent cation ionophore, extracted from
Streptomyces chartrecensis. With wide variety of antimicrobial activities, it also exhibits …