Hashimoto thyroiditis: clinical and diagnostic criteria

P Caturegli, A De Remigis, NR Rose - Autoimmunity reviews, 2014 - Elsevier
Hashimoto thyroiditis (HT), now considered the most common autoimmune disease, was
described over a century ago as a pronounced lymphoid goiter affecting predominantly …

Mechanisms in endocrinology: autoimmune thyroid disease: old and new players

G Effraimidis, WM Wiersinga - European journal of …, 2014 - academic.oup.com
The last 10 years have seen some progress in understanding the etiology of autoimmune
thyroid disease (AITD). The female preponderance can now be explained–at least in part …

Prediction and prevention of autoimmune disease in the 21st century: a review and preview

NR Rose - American journal of epidemiology, 2016 - academic.oup.com
Autoimmune diseases represent a family of at least 80 illnesses that share a common
pathogenesis: an immune-mediated attack on the body's own organs. Collectively …

Thyrotropin-blocking autoantibodies and thyroid-stimulating autoantibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to …

SM McLachlan, B Rapoport - Thyroid, 2013 - liebertpub.com
Background: Thyrotropin receptor (TSHR) antibodies that stimulate the thyroid (TSAb) cause
Graves' hyperthyroidism and TSHR antibodies which block thyrotropin action (TBAb) are …

Autoantibodies targeting intracellular and extracellular proteins in autoimmunity

PD Burbelo, MJ Iadarola, JM Keller… - Frontiers in …, 2021 - frontiersin.org
Detecting autoantibodies provides foundational information for the diagnosis of most
autoimmune diseases. An important pathophysiological distinction is whether …

Xerostomia due to systemic disease: a review of 20 conditions and mechanisms

H Mortazavi, M Baharvand, A Movahhedian… - Annals of medical and …, 2014 - ajol.info
Xerostomia is a common complaint of nearly half of the elderly population and about one‑
fifth of younger adults. It causes several signs and symptoms, and compromise oral functions …

Development of autoantibodies precedes clinical manifestations of autoimmune diseases: a comprehensive review

WT Ma, C Chang, ME Gershwin, ZX Lian - Journal of autoimmunity, 2017 - Elsevier
The etiology of autoimmune diseases is due to a combination of genetic predisposition and
environmental factors that alter the expression of immune regulatory genes through various …

Hashimoto's thyroiditis: celebrating the centennial through the lens of the Johns Hopkins hospital surgical pathology records

P Caturegli, A De Remigis, K Chuang, M Dembele… - Thyroid, 2013 - liebertpub.com
Hashimoto's thyroiditis is now considered the most prevalent autoimmune disease, as well
as the most common endocrine disorder. It was initially described in 1912, but only rarely …

Clinical implications of shared genetics and pathogenesis in autoimmune diseases

A Zhernakova, S Withoff, C Wijmenga - Nature Reviews Endocrinology, 2013 - nature.com
Many endocrine diseases, including type 1 diabetes mellitus, Graves disease, Addison
disease and Hashimoto disease, originate as an autoimmune reaction that affects disease …

[HTML][HTML] Clinical practice guidelines for the management of hypothyroidism

G Brenta, M Vaisman, JA Sgarbi… - … de Endocrinologia & …, 2013 - SciELO Brasil
INTRODUCTION: Hypothyroidism has long been known for its effects on different organ
systems, leading to hypometabolism. However, subclinical hypothyroidism, its most …