Tissue optical clearing technique provides a prospective solution for the application of
advanced optical methods in life sciences. This paper gives a review of recent …

Second Harmonic Generation Imaging Microscopy: Applications to Diseases Diagnostics |
Analytical Chemistry ACS ACS Publications C&EN CAS Find my institution Log In Analytical …

Understanding the structure-function relationships at cellular, circuit, and organ-wide scale
requires 3D anatomical and phenotypical maps, currently unavailable for many organs …

Aging is often accompanied by declines in physical functioning which impedes older adults'
quality of life, sense of independence, and ability to perform daily tasks. Age-related …

Multiphoton microscopy of collagen hydrogels produces second harmonic generation (SHG)
and two-photon fluorescence (TPF) images, which can be used to noninvasively study gel …

In this review, the authors discuss the underlying principles of SHG and specific factors that
affect the generation properties and describe the essential components of a SHG instrument …

In this article, we discuss the optical immersion method based on refractive index matching
of scatterers (eg, collagen, elastin fibers, cells and cell compartments) and the ground …

This paper aims to review recent progress in optical clearing of the skin and over naturally
turbid biological tissues and blood using this technique in vivo and in vitro with multiphoton …

Second‐harmonic generation (SHG) microscopy is a fantastic tool for imaging collagen and
probing its hierarchical organization from molecular scale up to tissue architectural level. In …

Although noninvasive, continuous monitoring of glucose concentration in blood and tissues
is one of the most challenging areas in medicine, a wide range of optical techniques has …