Mycobacterium tuberculosis infection of host cells in space and time
C Bussi, MG Gutierrez - FEMS microbiology reviews, 2019 - academic.oup.com
Tuberculosis (TB) caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb)
remains one of the deadliest infectious diseases with over a billion deaths in the past 200 …
remains one of the deadliest infectious diseases with over a billion deaths in the past 200 …
A comprehensive review of autophagy and its various roles in infectious, non-infectious, and lifestyle diseases: current knowledge and prospects for disease …
Autophagy (self-eating) is a conserved cellular degradation process that plays important
roles in maintaining homeostasis and preventing nutritional, metabolic, and infection …
roles in maintaining homeostasis and preventing nutritional, metabolic, and infection …
Advancing host-directed therapy for tuberculosis
RS Wallis, R Hafner - Nature Reviews Immunology, 2015 - nature.com
Improved treatments are needed for nearly all forms of Mycobacterium tuberculosis infection.
Adjunctive host-directed therapies have the potential to shorten tuberculosis treatment …
Adjunctive host-directed therapies have the potential to shorten tuberculosis treatment …
Therapeutic targeting of autophagy in disease: biology and pharmacology
Y Cheng, X Ren, WN Hait, JM Yang, Q Ma - Pharmacological reviews, 2013 - Elsevier
Autophagy, a process of self-digestion of the cytoplasm and organelles through which
cellular components are recycled for reuse or energy production, is an evolutionarily …
cellular components are recycled for reuse or energy production, is an evolutionarily …
Autophagy: A new strategy for host-directed therapy of tuberculosis
Tuberculosis (TB), which is primarily caused by the major etiologic agent Mycobacterium
tuberculosis (Mtb), remains a serious infectious disease worldwide. Recently, much effort …
tuberculosis (Mtb), remains a serious infectious disease worldwide. Recently, much effort …
Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action
The current standard of treatment against tuberculosis consists of a cocktail of first-line
drugs, including isoniazid and pyrazinamide. Although these drugs are known to be …
drugs, including isoniazid and pyrazinamide. Although these drugs are known to be …
[HTML][HTML] Vitamin D levels and COVID-19 susceptibility: is there any correlation?
Abstract Coronavirus disease (COVID-19) is a major pandemic and now a leading cause of
death worldwide. Currently, no drugs/vaccine is available for the treatment of this disease …
death worldwide. Currently, no drugs/vaccine is available for the treatment of this disease …
A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: Immunological, physical performance, and cognitive …
Inhibition of the mechanistic target of rapamycin (mTOR) pathway by rapamycin (RAPA), an
FDA-approved immunosuppressive drug used as a clinical therapy to prevent solid organ …
FDA-approved immunosuppressive drug used as a clinical therapy to prevent solid organ …
Vitamin D and immune function: autocrine, paracrine or endocrine?
M Hewison - Scandinavian Journal of Clinical and Laboratory …, 2012 - Taylor & Francis
Prominent amongst the non-classical effects of vitamin D is its interaction with the immune
system. Although this has been recognized for many years, it is only through recent studies …
system. Although this has been recognized for many years, it is only through recent studies …
Mycobacterial signaling through toll-like receptors
J Basu, DM Shin, EK Jo - Frontiers in cellular and infection …, 2012 - frontiersin.org
Studies over the past decade have helped to decipher molecular networks dependent on
Toll-like receptor (TLR) signaling, in mycobacteria-infected macrophages. Stimulation of …
Toll-like receptor (TLR) signaling, in mycobacteria-infected macrophages. Stimulation of …