Therapeutic potential of stilbenes in neuropsychiatric and neurological disorders: A comprehensive review of preclinical and clinical evidence

K Socała, E Żmudzka, K Lustyk, M Zagaja… - Phytotherapy …, 2024 - Wiley Online Library
Neuropsychiatric disorders are anticipated to be a leading health concern in the near future,
emphasizing an outstanding need for the development of new effective therapeutics to treat …

[HTML][HTML] Role of Plant Phytochemicals: Resveratrol, Curcumin, Luteolin and Quercetin in Demyelination, Neurodegeneration, and Epilepsy

M Grabarczyk, W Justyńska, J Czpakowska… - Antioxidants, 2024 - mdpi.com
Polyphenols are an important group of biologically active compounds present in almost all
food sources of plant origin and are primarily known for their anti-inflammatory and …

AHR/ROS-mediated mitochondria apoptosis contributes to benzo [a] pyrene-induced heart defects and the protective effects of resveratrol

Y Huang, J Zhang, Y Tao, C Ji, S Aniagu, Y Jiang… - Toxicology, 2021 - Elsevier
Abstract Benzo [a] pyrene (BaP), a prototypical polycyclic aromatic hydrocarbon, is widely
present in the environment. BaP-induced heart defects have been frequently reported, but …

Neurobehavioral impairments from chromium exposure: insights from a zebrafish model and drug validation

S Boopathi, B Haridevamuthu, A Gandhi… - … and Physiology Part C …, 2024 - Elsevier
We have developed a zebrafish model to explore the alterations in neurobehaviors resulting
from both acute and chronic exposure to chromium (Cr). Zebrafish exposed to half (HC …

[HTML][HTML] Resveratrol ameliorates penconazole-induced cardiotoxicity by inhibition of oxidative stress and apoptosis in zebrafish larvae

X Jiang, J Wang, J Liu, H Zhu, J Hu, X Sun… - … and Environmental Safety, 2023 - Elsevier
Penconazole (PEN) is a typical systemic triazole fungicide with cardiac toxic effects.
Resveratrol (RES) is a natural polyphenolic phytochemical with antioxidation properties …

Resveratrol-loaded glutathione-coated collagen nanoparticles attenuate acute seizures by inhibiting HMGB1 and TLR-4 in the hippocampus of mice

MA Siddiqui, M Asad, J Akhter, U Hoda… - ACS Chemical …, 2022 - ACS Publications
Epilepsy is a relatively complicated neurological disorder that results in seizures. The use of
resveratrol in treating seizures has been reported in recent studies. However, the low …

[HTML][HTML] Synergistic protective effects of folic acid and resveratrol against fine particulate matter-induced heart malformations in zebrafish embryos

J Chen, M Zhang, H Zou, S Aniagu, Y Jiang… - … and environmental safety, 2022 - Elsevier
Ambient fine particulate matter (PM2. 5) is a major environmental health problem worldwide,
and recent studies indicate that maternal PM2. 5 exposure is closely associated with …

Chemically-induced epileptic seizures in zebrafish: A systematic review

R Chitolina, M Gallas-Lopes, CG Reis, R Benvenutti… - Epilepsy Research, 2023 - Elsevier
The use of zebrafish as a model organism is gaining evidence in the field of epilepsy as it
may help to understand the mechanisms underlying epileptic seizures. As zebrafish assays …

Curcumin micronization by supercritical fluid: In vitro and in vivo biological relevance

A Sachett, M Gallas-Lopes, R Benvenutti… - Industrial Crops and …, 2022 - Elsevier
Curcumin, a polyphenol extracted from the rhizome of Curcuma longa L.(Zingiberaceae), is
shown to have antioxidant, anti-inflammatory, neuroprotective, anxiolytic, and …

Optimization of a locomotion-based zebrafish seizure model

PAG Shaw, SK Panda, A Stanca, W Luyten - Journal of neuroscience …, 2022 - Elsevier
Background Locomotor assays in zebrafish have emerged as a screening test in early drug
discovery for antiseizure compounds. However, parameters differ considerably between …