Malaria is one of the most devastating infectious diseases of humans. It is problematic
clinically and economically as it prevails in poorer countries and regions, strongly hindering …

Plasmodium vivax is the most widespread human malaria parasite, in part because it can
form latent liver stages known as hypnozoites after transmission by female anopheline …

Plasmodium vivax malaria is characterized by periodic relapses of symptomatic blood stage
parasite infections likely initiated by activation of dormant liver stage parasites …

The eradication of malaria will only be possible if effective, well-tolerated medicines kill
hypnozoites in vivax and ovale malaria, and thus prevent relapses in patients. Despite …

Recurrence of malaria symptoms after treatment constitutes one of the major factors affecting
malaria control in the population. The transmission of malaria will persist in the population, if …

Malaria caused by Plasmodium species and transmitted by Anopheles mosquitoes affects
large human populations, while Ixodes ticks transmit Babesia species and cause …

Humans have lived in tenuous battle with malaria over millennia. Today, while much of the
world is free of the disease, areas of South America, Asia, and Africa still wage this war with …

In this study, a new mathematical model for malaria dynamics featuring all the three
categories of recurrent malaria—recrudescence, relapse and re-infection—is presented and …

The neglected but highly prevalent Plasmodium vivax in South-east Asia and South America
poses a great challenge, with regards to long-term in-vitro culturing and heavily limited …

Abstract Development of a protective and broadly-acting vaccine against the most widely
distributed human malaria parasite, Plasmodium vivax, will be a major step towards malaria …