[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance

H Marshall, NJ Stewart, HF Chan, M Rao… - Progress in Nuclear …, 2021 - Elsevier
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …

The future of MRI in radiation therapy: Challenges and opportunities for the MR community

RJ Goodburn, MEP Philippens… - Magnetic resonance …, 2022 - Wiley Online Library
Radiation therapy is a major component of cancer treatment pathways worldwide. The main
aim of this treatment is to achieve tumor control through the delivery of ionizing radiation …

The VAMPIRE challenge: a multi‐institutional validation study of CT ventilation imaging

J Kipritidis, BA Tahir, G Cazoulat, MS Hofman… - Medical …, 2019 - Wiley Online Library
Purpose CT ventilation imaging (CTVI) is being used to achieve functional avoidance lung
cancer radiation therapy in three clinical trials (NCT02528942, NCT02308709 …

Chronic obstructive pulmonary disease: thoracic CT texture analysis and machine learning to predict pulmonary ventilation

A Westcott, DPI Capaldi, DG McCormack, AD Ward… - Radiology, 2019 - pubs.rsna.org
Background Fixed airflow limitation and ventilation heterogeneity are common in chronic
obstructive pulmonary disease (COPD). Conventional noncontrast CT provides airway and …

Large-scale investigation of deep learning approaches for ventilated lung segmentation using multi-nuclear hyperpolarized gas MRI

JR Astley, AM Biancardi, PJC Hughes, H Marshall… - Scientific Reports, 2022 - nature.com
Respiratory diseases are leading causes of mortality and morbidity worldwide. Pulmonary
imaging is an essential component of the diagnosis, treatment planning, monitoring, and …

Deep learning-based computed tomography perfusion mapping (DL-CTPM) for pulmonary CT-to-perfusion translation

G Ren, J Zhang, T Li, H Xiao, LY Cheung… - International Journal of …, 2021 - Elsevier
Purpose Our purpose was to develop a deep learning–based computed tomography (CT)
perfusion mapping (DL-CTPM) method that synthesizes lung perfusion images from CT …

Pulmonary ventilation maps generated with free-breathing proton MRI and a deep convolutional neural network

DPI Capaldi, F Guo, L Xing, G Parraga - Radiology, 2021 - pubs.rsna.org
Background Hyperpolarized noble gas MRI helps measure lung ventilation, but clinical
translation remains limited. Free-breathing proton MRI may help quantify lung function using …

Assessment of the influence of lung inflation state on the quantitative parameters derived from hyperpolarized gas lung ventilation MRI in healthy volunteers

PJC Hughes, L Smith, HF Chan… - Journal of Applied …, 2019 - journals.physiology.org
In this study, the effect of lung volume on quantitative measures of lung ventilation was
investigated using MRI with hyperpolarized 3He and 129Xe. Six volunteers were imaged …

PhysVENeT: a physiologically-informed deep learning-based framework for the synthesis of 3D hyperpolarized gas MRI ventilation

JR Astley, AM Biancardi, H Marshall, LJ Smith… - Scientific Reports, 2023 - nature.com
Functional lung imaging modalities such as hyperpolarized gas MRI ventilation enable
visualization and quantification of regional lung ventilation; however, these techniques …

Deep learning in structural and functional lung image analysis

JR Astley, JM Wild, BA Tahir - The British Journal of Radiology, 2022 - academic.oup.com
The recent resurgence of deep learning (DL) has dramatically influenced the medical
imaging field. Medical image analysis applications have been at the forefront of DL research …