Substance P (SP) and neurotensin (NT) are neuropeptides isolated in the periphery and in the central nervous system. They are involved in various regulatory processes in the …
Stress during postnatal development is associated with an increased risk for depression, anxiety disorders, and substance abuse later in life, almost as if mental illness is able to be …
MM Boules, P Fredrickson, AM Muehlmann… - Behavioral …, 2014 - mdpi.com
Neurotensin (NT) is a neuropeptide that is closely associated with, and is thought to modulate, dopaminergic and other neurotransmitter systems involved in the …
G Kyriatzis, M Khrestchatisky, L Ferhat… - Current …, 2024 - ingentaconnect.com
Neurotensin (NT) is a 13-amino acid neuropeptide widely distributed in the CNS that has been involved in the pathophysiology of many neural and psychiatric disorders. There are …
Neurotensin is an endogenous neuropeptide that has significant interactions with monoamine neurotransmitter systems. To date, neurotensin NTS 1 receptor agonists, such …
CA Vadnie, J Ayers-Ringler, A Oliveros… - Behavioural brain …, 2016 - Elsevier
Although neurotensin (NT) analogs are known to produce antipsychotic-like effects, the therapeutic possibility of a brain penetrant NTS1 agonist in treating psychiatric disorders has …
AA Keiser, KS Matazel, MK Esser, D Feifel… - Experimental and …, 2014 - psycnet.apa.org
Agonists for the neurotensin NTS 1 receptor consistently exhibit antipsychotic effects in animal models without producing catalepsy, suggesting that NTS 1-receptor agonists may …
ABSTRACT Preclinical Research Neurotensin is a nonbrain penetrant neuropeptide neurotransmitter that alters dopaminergic and serotonergic neurotransmission. Previous …
Methamphetamine (METH) is a psychostimulant that exhibits significant abuse potential. Although METH addiction is a major health and societal concern, no drug is currently …