[HTML][HTML] Biological drug and drug delivery-mediated immunotherapy

Q Xiao, X Li, Y Li, Z Wu, C Xu, Z Chen, W He - Acta Pharmaceutica Sinica B, 2021 - Elsevier
The initiation and development of major inflammatory diseases, ie, cancer, vascular
inflammation, and some autoimmune diseases are closely linked to the immune system …

Design of experiments (DoE) to develop and to optimize nanoparticles as drug delivery systems

MT Luiz, JSR Viegas, JP Abriata, F Viegas… - European Journal of …, 2021 - Elsevier
Nanotechnology has been widely applied to develop drug delivery systems to improve
therapeutic performance. The effectiveness of these systems is intrinsically related to their …

[HTML][HTML] Liposome-loaded polymeric microneedles for enhanced skin deposition of rifampicin

QK Anjani, AK Pandya, S Demartis… - International Journal of …, 2023 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) is a prevailing bacterial pathogen
linked to superficial skin and soft tissue infections (SSTIs). Rifampicin (RIF), a potent …

Co-Delivery of erlotinib and resveratrol via nanostructured lipid Carriers: a synergistically promising approach for cell proliferation prevention and ROS-Mediated …

L Asadollahi, A Mahoutforoush, SS Dorreyatim… - International journal of …, 2022 - Elsevier
Cancer treatments are always associated with various challenges, and scientists are
constantly trying to find new therapies and methods. Erlotinib (ELT) is a well-known …

Quality by design approach in liposomal formulations: Robust product development

W Alshaer, H Nsairat, Z Lafi, OM Hourani, A Al-Kadash… - Molecules, 2022 - mdpi.com
Nanomedicine is an emerging field with continuous growth and differentiation. Liposomal
formulations are a major platform in nanomedicine, with more than fifteen FDA-approved …

A quality by design (QbD) approach in pharmaceutical development of lipid-based nanosystems: A systematic review

DM Zagalo, BMA Silva, C Silva, S Simoes… - Journal of Drug Delivery …, 2022 - Elsevier
Over the last few decades, there has been an impressive progress on developing novel drug
delivery systems and targeted therapies through the use of Nanotechnology. In particular …

Role of solid lipid nanoparticles as drug delivery vehicles on the pharmacokinetic variability of Erlotinib HCl

R Rampaka, K Ommi, N Chella - Journal of Drug Delivery Science and …, 2021 - Elsevier
Abstract Background and objectives Erlotinib HCl is approved for the treatment of metastatic
non-small cell lung cancer. Owing to its poor aqueous solubility and presystemic …

Inhalation of sustained release microparticles for the targeted treatment of respiratory diseases

G Pulivendala, S Bale, C Godugu - Drug delivery and translational …, 2020 - Springer
Delivering drugs through inhalation for systemic and local applications has been in practice
since several decades to treat various diseases. In recent times, inhalation drug delivery is …

Liposomal form of erlotinib for local inhalation administration and efficiency of its transport to the lungs

J Szabová, O Mišík, J Fučík, K Mrázová… - International Journal of …, 2023 - Elsevier
This contribution is focused on the preparation of a liposomal drug delivery system of
erlotinib resisting the nebulization process that could be used for local treatment of non …

Cytotoxic Evaluation and Anti-Angiogenic Effects of Two Furano-Sesquiterpenoids from Commiphora myrrh Resin

A S. Alqahtani, FA Nasr, OM Noman, M Farooq… - Molecules, 2020 - mdpi.com
Commiphora myrrh resin (Myrrh) has been used in traditional Arabic medicine to treat
various inflammatory diseases. Two furano-sesquiterpenoids, 2-methoxyfuranodiene (CM1) …