Large-vessel vasculitis

D Pugh, M Karabayas, N Basu, MC Cid… - Nature Reviews …, 2021 - nature.com
Large-vessel vasculitis (LVV) manifests as inflammation of the aorta and its major branches
and is the most common primary vasculitis in adults. LVV comprises two distinct conditions …

Takayasu arteritis: advanced understanding is leading to new horizons

E Tombetti, JC Mason - Rheumatology, 2019 - academic.oup.com
Although outcomes in Takayasu arteritis (TAK) are improving, diagnosis is typically delayed
and significant arterial injury accrues. While wider use of non-invasive imaging is impacting …

Patterns of arterial disease in Takayasu arteritis and giant cell arteritis

KB Gribbons, C Ponte, S Carette… - Arthritis care & …, 2020 - Wiley Online Library
Objective To identify and validate, using computer‐driven methods, patterns of arterial
disease in Takayasu arteritis (TAK) and giant cell arteritis (GCA). Methods Patients with TAK …

Sex differences in pediatric rheumatology

M Cattalini, M Soliani, MC Caparello… - Clinical reviews in allergy & …, 2019 - Springer
Autoimmune diseases affect up to 10% of the world's population and, as a whole, they are
far more common in females, although differences exist according to the single disease and …

A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis

M Munz, C Willenborg, GM Richter… - Human molecular …, 2017 - academic.oup.com
Periodontitis is one of the most common inflammatory diseases, with a prevalence of 11%
worldwide for the severe forms and an estimated heritability of 50%. The disease is …

Updates in pathophysiology, diagnosis and management of Takayasu arteritis

R Serra, L Butrico, F Fugetto, MD Chibireva… - Annals of Vascular …, 2016 - Elsevier
Background Takayasu arteritis (TA) is a rare, systemic, inflammatory vasculitis of
granulomatous nature, and still of unknown etiology. It mainly involves the aorta and its …

[HTML][HTML] A genetic variant in IL-6 lowering its expression is protective for critical patients with COVID-19

B Gong, L Huang, Y He, W Xie, Y Yin, Y Shi… - … and Targeted Therapy, 2022 - nature.com
Abstract Critical coronavirus disease 2019 (COVID-19) is associated with high mortality and
potential genetic factors have been reported to be involved in the development of critical …

[PDF][PDF] Genetic architecture of gene expression in European and African Americans: an eQTL mapping study in GENOA

L Shang, JA Smith, W Zhao, M Kho, ST Turner… - The American Journal of …, 2020 - cell.com
Most existing expression quantitative trait locus (eQTL) mapping studies have been focused
on individuals of European ancestry and are underrepresented in other populations …

[HTML][HTML] Innate and adaptive immunity in giant cell arteritis

M Akiyama, S Ohtsuki, GJ Berry, DH Liang… - Frontiers in …, 2021 - frontiersin.org
Autoimmune diseases can afflict every organ system, including blood vessels that are
critically important for host survival. The most frequent autoimmune vasculitis is giant cell …

Prevalence, incidence, and disease characteristics of Takayasu arteritis by ethnic background: data from a large, population‐based cohort resident in southern …

B Gudbrandsson, Ø Molberg, T Garen… - Arthritis care & …, 2017 - Wiley Online Library
Objective To study the epidemiology and clinical characteristics of Takayasu arteritis (TAK)
in southeast Norway (population 2.8 million). Methods All study area hospital databases …