[HTML][HTML] The multi-faceted consequences of NRF2 activation throughout carcinogenesis
The oxidative balance of a cell is maintained by the Kelch-like ECH-associated protein 1
(KEAP1)/nuclear factor erythroid 2-related factor 2 (NRF2) pathway. This cytoprotective …
(KEAP1)/nuclear factor erythroid 2-related factor 2 (NRF2) pathway. This cytoprotective …
[HTML][HTML] Keap1-Nrf2 pathway: a key mechanism in the occurrence and development of cancer
F Chen, M Xiao, S Hu, M Wang - Frontiers in Oncology, 2024 - ncbi.nlm.nih.gov
Abstract The Keap1-Nrf2 signaling pathway is a major regulator of the cytoprotective
response, participating in endogenous and exogenous stress caused by ROS (reactive …
response, participating in endogenous and exogenous stress caused by ROS (reactive …
The protective effect of crocin against testicular toxicity induced by ionizing radiation via AKT/FOXO pathway
MM El‐Sheikh, MM Aziz… - Environmental …, 2023 - Wiley Online Library
Crocin, a pharmacologically active component of Crocus sativus L.(saffron), has been
informed to be beneficial in the treatment of stress‐related oxidative impairment. In the …
informed to be beneficial in the treatment of stress‐related oxidative impairment. In the …
Therapeutic Effects of Natural Products in the Treatment of Chronic Diseases: The Role in Regulating KEAP1–NRF2 Pathway
Y Li, X Wang, S Li, L Wang, N Ding… - The American Journal of …, 2025 - World Scientific
Oxidative stress represents a pivotal mechanism in the pathogenesis of numerous chronic
diseases. The Kelch-like ECH-associated protein 1–transcription factor NF-E2 p45-related …
diseases. The Kelch-like ECH-associated protein 1–transcription factor NF-E2 p45-related …
A recombinant plasmid encoding human hepatocyte growth factor promotes healing of combined radiation-trauma skin injury involved in regulating Nrf2 pathway in …
D Li, Y Lu, F Xiao, X Cheng, C Hu, X Zhu… - Journal of Radiation …, 2024 - academic.oup.com
Combined radiation-trauma skin injury represents a severe and intractable condition that
urgently requires effective therapeutic interventions. In this context, hepatocyte growth factor …
urgently requires effective therapeutic interventions. In this context, hepatocyte growth factor …
Targeted delivery of napabucasin with radiotherapy improves outcomes in diffuse midline glioma
Background Diffuse midline glioma (DMG) is the most aggressive primary brain tumor in
children. All previous studies examining the role of systemic agents have failed to …
children. All previous studies examining the role of systemic agents have failed to …