Dry powder inhalation therapy has been shown to be an effective method for treating
respiratory diseases like asthma, Chronic Obstructive Pulmonary Diseases and Cystic …

The early and correct assessment of psychomotor agitation (PMA) is essential to ensure
prompt intervention by healthcare professionals to improve the patient's condition, protect …

Importance Acute agitation is common in patients with bipolar disorder and requires urgent
management to relieve distress and to prevent escalation to aggressive behavior. Objective …

Heart failure causes considerable morbidity and mortality worldwide. Clinically applied
drugs for the treatment of heart failure are still severely limited by poor delivery efficiency to …

Objective: Determine if sublingual dexmedetomidine, a selective α 2 adrenergic receptor
agonist, reduces symptoms of acute agitation associated with schizophrenia or …

Introduction The objective was to use the evidence-based medicine metrics of number
needed to treat, number needed to harm, and likelihood to be helped or harmed to appraise …

Introduction Noncommunicable diseases (NCDs) are the leading cause of morbidity and
mortality in the Association of Southeast Asian Nations (ASEAN) member states. Progress …

Background: Multiple sclerosis (MS) treatment has radically improved over the last years;
however, MS symptom management is still challenging. The novel Spasticity-Plus syndrome …

Psychomotor agitation is characterised by an increase in psychomotor activity, restlessness
and irritability. People with psychomotor agitation respond by over-reacting to both intrinsic …

Background Dominant-submissive relationships depend upon functionality of the neural
circuits involving monoaminergic neurotransmission. Behavioral profiles of selectively bred …