[HTML][HTML] Liver fibrosis is a common pathological change in the liver of dairy cows with fatty liver

C Zhang, Q Shao, M Liu, X Wang, JJ Loor, Q Jiang… - Journal of Dairy …, 2023 - Elsevier
Fatty liver (ie, hepatic lipidosis) is a prevalent metabolic disorder in dairy cows during the
transition period, characterized by excess hepatic accumulation of triglyceride (TG), tissue …

[HTML][HTML] Aspects of transition cow metabolomics—Part III: Alterations in the metabolome of liver and blood throughout the transition period in cows with different liver …

M Schären, B Riefke, M Slopianka, M Keck… - Journal of Dairy …, 2021 - Elsevier
The liver plays a central role in the postpartum (PP) energy metabolism of the transition dairy
cow; however, studies describing the liver metabolome during this period were lacking. The …

[HTML][HTML] Aspects of transition cow metabolomics—Part I: Effects of a metaphylactic butaphosphan and cyanocobalamin treatment on the metabolome in liver, blood …

M Schären, T Snedec, B Riefke, M Slopianka… - Journal of Dairy …, 2021 - Elsevier
Dairy cows in modern production systems are at risk to develop metabolic disorders during
the transition period. Reasons for individual differences in susceptibility, as well as the …

[HTML][HTML] Influence of the concentrate inclusion level in a grass silage–based diet on hepatic transcriptomic profiles in Holstein-Friesian dairy cows in early lactation

Z Cheng, MW Little, C Ferris, H Takeda… - Journal of Dairy …, 2023 - Elsevier
Excessive negative energy balance in early lactation is linked to an increased disease risk
but may be mitigated by appropriate nutrition. The liver plays central roles in both …

Qualitative and quantitative changes in total lipid concentration and lipid fractions in liver tissue of periparturient German Holstein dairy cows of two age groups

KB Theinert, T Snedec, F Pietsch, S Theile… - Frontiers in Veterinary …, 2022 - frontiersin.org
Fatty liver syndrome (FLS) is a common disease in high-producing dairy cows. Studies in
humans suggest that the different hepatic lipid fractions play a role in this context. In dairy …

A potential gateway to understanding liver disease development: peripartum lipid fluctuations in dairy cows

L Vogel, M Güttler, KB Theinert, T Snedec… - Frontiers in Cell and …, 2024 - frontiersin.org
Current lifestyles are leading to a worldwide increase in metabolic liver diseases that favor
the development of liver disease. Changes in hepatocytes are caused by altered lipid …

Die Leberverfettung der Milchkuh: Teil 1

H Martens - Tierärztliche Praxis Ausgabe G: Großtiere/Nutztiere, 2023 - thieme-connect.com
Die Fettleber von Milchkühen ist seit vielen Jahren bekannt und bedingt durch eine
vermehrte Aufnahme von freien Fettsäuren (NEFA) in die Leberzellen und unzureichender …

[HTML][HTML] Effects of an intensive experimental protocol on health, fertility, and production in transition dairy cows

T Snedec, L Bittner-Schwerda, F Rachidi… - Journal of Dairy …, 2022 - Elsevier
Animal experimentation is required to investigate complex physiological relationships and
facilitates development of evidence-based knowledge. However, experimental protocols can …

Die Leberverfettung der Milchkuh: Teil 2

H Martens - Tierärztliche Praxis Ausgabe G: Großtiere/Nutztiere, 2023 - thieme-connect.com
Die Leberverfettung bei Milchkühen ist das Ergebnis eines gestörten Gleichgewichts
zwischen der Aufnahme von freien Fettsäuren (NEFA) in die Leberzellen im Verhältnis zur …

Changes of the liver metabolome following an intravenous lipopolysaccharide injection in Holstein cows supplemented with dietary carnitine

W Xu, S Grindler, Á Kenéz, S Dänicke, J Frahm… - Journal of Animal …, 2022 - Springer
Background Carnitine facilitates the flux of long-chain fatty acids for hepatic mitochondrial
beta-oxidation, which acts to ameliorate the negative energy balance commonly affecting …