[HTML][HTML] Perspectives on plastic waste management: challenges and possible solutions to ensure its sustainable use

AD Macheca, B Mutuma, JL Adalima, E Midheme… - Recycling, 2024 - mdpi.com
The pollution of the environment by plastics is a global problem that is real and needs to be
resolved urgently. The authors argue that banning the use of plastic is not a reasonable and …

In-vitro in-vivo correlation (IVIVC) in nanomedicine: Is protein corona the missing link?

P Jain, RS Pawar, RS Pandey, J Madan, S Pawar… - Biotechnology …, 2017 - Elsevier
One of the unmet challenges in nanotechnology is to understand and establish the
relationship between physicochemical properties of nanoparticles (NPs) and its biological …

Liposomal delivery of CRISPR/Cas9

S Zhen, X Li - Cancer gene therapy, 2020 - nature.com
Liposomes are one of the most widely investigated carriers for CRISPR/Cas9 delivery. The
surface properties of liposomal carriers, including the surface charge, PEGylation, and …

Particle tracking in drug and gene delivery research: State-of-the-art applications and methods

BS Schuster, LM Ensign, DB Allan, JS Suk… - Advanced drug delivery …, 2015 - Elsevier
Particle tracking is a powerful microscopy technique to quantify the motion of individual
particles at high spatial and temporal resolution in complex fluids and biological specimens …

Polymeric siRNA gene delivery–transfection efficiency versus cytotoxicity

A Kargaard, JPG Sluijter, B Klumperman - Journal of controlled release, 2019 - Elsevier
Within the field of gene therapy, there is a considerable need for the development of non-
viral vectors that are able to compete with the efficiency obtained by viral vectors, while …

Nanomedicine-based intraperitoneal therapy for the treatment of peritoneal carcinomatosis—Mission possible?

GR Dakwar, M Shariati, W Willaert, W Ceelen… - Advanced drug delivery …, 2017 - Elsevier
Intraperitoneal (IP) drug delivery represents an attractive strategy for the local treatment of
peritoneal carcinomatosis (PC). Over the past decade, a lot of effort has been put both in the …

Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy

I Negwer, A Best, M Schinnerer, O Schäfer… - Nature …, 2018 - nature.com
Nanocarrier-based drug delivery is a promising therapeutic approach that offers unique
possibilities for the treatment of various diseases. However, inside the blood stream …

Bio-inspired pulmonary surfactant-modified nanogels: A promising siRNA delivery system

L De Backer, K Braeckmans, MCA Stuart… - Journal of controlled …, 2015 - Elsevier
Inhalation therapy with small interfering RNA (siRNA) is a promising approach in the
treatment of pulmonary disorders. However, clinical translation is severely limited by the lack …

Cationic amphiphilic drugs boost the lysosomal escape of small nucleic acid therapeutics in a nanocarrier-dependent manner

T Van de Vyver, B Bogaert, L De Backer, F Joris… - ACS …, 2020 - ACS Publications
Small nucleic acid (NA) therapeutics, such as small interfering RNA (siRNA), are generally
formulated in nanoparticles (NPs) to overcome the multiple extra-and intracellular barriers …

Shining light on polymeric drug nanocarriers with fluorescence correlation spectroscopy

S Schmitt, L Nuhn, M Barz, HJ Butt… - Macromolecular Rapid …, 2022 - Wiley Online Library
The use of nanoparticles as carriers is an extremely promising way for administration of
therapeutic agents, such as drug molecules, proteins, and nucleic acids. Such nanocarriers …