Preeclampsia: pathogenesis, prevention, and long-term complications

B Jim, SA Karumanchi - Seminars in nephrology, 2017 - Elsevier
Preeclampsia continues to afflict 5% to 8% of all pregnancies throughout the world and is
associated with significant morbidity and mortality to the mother and the fetus. Although the …

A critical review of early-onset and late-onset preeclampsia

D Raymond, E Peterson - Obstetrical & gynecological survey, 2011 - journals.lww.com
Preeclampsia is a leading cause of pregnancy-related morbidity and mortality in the United
States. In the past 30 years, a large amount of research has been performed to investigate …

The placenta in preeclampsia

JM Roberts, C Escudero - Pregnancy Hypertension: An International …, 2012 - Elsevier
The root cause of preeclampsia is the placenta. Preeclampsia begins to abate with the
delivery of the placenta and can occur in the absence of a fetus but with the presence of …

Angiogenic factors and preeclampsia

SE Maynard, SA Karumanchi - Seminars in nephrology, 2011 - Elsevier
Preeclampsia, a hypertensive disorder peculiar to pregnancy, is a systemic syndrome that
appears to originate in the placenta and is characterized by widespread maternal …

Intrauterine growth restriction: new concepts in antenatal surveillance, diagnosis, and management

F Figueras, J Gardosi - American journal of obstetrics and gynecology, 2011 - Elsevier
Intrauterine growth restriction (IUGR) remains one of the main challenges in maternity care.
Improvements have to start from a better definition of IUGR, applying the concept of the fetal …

Maternal cardiovascular function in normal pregnancy: evidence of maladaptation to chronic volume overload

K Melchiorre, R Sharma, A Khalil, B Thilaganathan - Hypertension, 2016 - Am Heart Assoc
The aim of this study was to investigate cardiac functional status in pregnancy using a
comprehensive approach taking into account the simultaneous changes in loading and …

Early and late preeclampsia: two different maternal hemodynamic states in the latent phase of the disease

H Valensise, B Vasapollo, G Gagliardi, GP Novelli - Hypertension, 2008 - Am Heart Assoc
Because early and late preeclampsia (PE) are thought to be different disease entities, we
compared maternal cardiac function at 24 weeks gestation in a group of normotensive …

Intrauterine growth restriction

R Resnik - Obstetrics & Gynecology, 2002 - Elsevier
Fetal intrauterine growth restriction presents a complex management problem for the
clinician. The failure of a fetus to achieve its growth potential imparts a significantly …

A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in …

R Romero, JK Nien, J Espinoza, D Todem… - The journal of …, 2008 - Taylor & Francis
Introduction. Accumulating evidence suggests that an imbalance between pro-angiogenic
(ie, vascular endothelial growth factor (VEGF) and placental growth factor (PlGF)) and anti …

[HTML][HTML] Toward a new taxonomy of obstetrical disease: improved performance of maternal blood biomarkers for the great obstetrical syndromes when classified …

R Romero, E Jung, T Chaiworapongsa, O Erez… - American journal of …, 2022 - Elsevier
Background The major challenge for obstetrics is the prediction and prevention of the great
obstetrical syndromes. We propose that defining obstetrical diseases by the combination of …