Treatment of rare factor deficiencies other than hemophilia
M Menegatti, F Peyvandi - Blood, The Journal of the American …, 2019 - ashpublications.org
The deficiency of fibrinogen, prothrombin, factor V (FV), FVII, FVIII, FIX, FX, FXI, and FXIII,
called rare coagulation disorders (RCDs), may result in coagulopathies leading to …
called rare coagulation disorders (RCDs), may result in coagulopathies leading to …
Molecular basis of rare congenital bleeding disorders
A Dorgalaleh, M Bahraini, M Shams, F Parhizkari… - Blood Reviews, 2023 - Elsevier
Rare bleeding disorders (RBDs), including factor (F) I, FII, FV, FVII, combined FV and FVIII
(CF5F8), FXI, FXIII and vitamin-K dependent coagulation factors (VKCF) deficiencies, are a …
(CF5F8), FXI, FXIII and vitamin-K dependent coagulation factors (VKCF) deficiencies, are a …
[HTML][HTML] Diagnosis and classification of congenital fibrinogen disorders: communication from the SSC of the ISTH
Congenital fibrinogen disorders (CFDs) are a heterogeneous group of rare inherited
abnormalities of blood coagulation 1. CFDs result from monoallelic or biallelic mutations in …
abnormalities of blood coagulation 1. CFDs result from monoallelic or biallelic mutations in …
Genetic Variants in the FGB and FGG Genes Mapping in the Beta and Gamma Nodules of the Fibrinogen Molecule in Congenital Quantitative Fibrinogen Disorders …
Fibrinogen is a hexameric plasmatic glycoprotein composed of pairs of three chains (Aα, Bβ,
and γ), which play an essential role in hemostasis. Conversion of fibrinogen to insoluble …
and γ), which play an essential role in hemostasis. Conversion of fibrinogen to insoluble …
Diagnosis and treatment of von Willebrand disease and rare bleeding disorders
G Castaman, S Linari - Journal of clinical medicine, 2017 - mdpi.com
Along with haemophilia A and B, von Willebrand disease (VWD) and rare bleeding
disorders (RBDs) cover all inherited bleeding disorders of coagulation. Bleeding tendency …
disorders (RBDs) cover all inherited bleeding disorders of coagulation. Bleeding tendency …
Disorders of fibrinogen and fibrinolysis
JE May, AS Wolberg, MY Lim - Hematology/Oncology …, 2021 - hemonc.theclinics.com
BACKGROUND Fibrinogen is a large (340 kDa) hexameric glycoprotein expressed by
hepatocytes. 1 Fibrinogen is encoded by 3 different genes (FGA, FGB, and FGG) and …
hepatocytes. 1 Fibrinogen is encoded by 3 different genes (FGA, FGB, and FGG) and …
Human fibrinogen: molecular and genetic aspects of congenital disorders
GL Tiscia, M Margaglione - International Journal of Molecular Sciences, 2018 - mdpi.com
Congenital fibrinogen disorders can be quantitative (afibrinogenemia, hypofibrinogenemia)
or functional (dysfibrinognemia). To date, several genetic variants have been identified in …
or functional (dysfibrinognemia). To date, several genetic variants have been identified in …
Mutations accounting for congenital fibrinogen disorders: an update
M Richard, D Celeny… - Seminars in Thrombosis …, 2022 - thieme-connect.com
Fibrinogen is a complex protein that plays a key role in the blood clotting process. It is a
hexamer composed of two copies of three distinct chains: Aα, Bβ, and γ encoded by three …
hexamer composed of two copies of three distinct chains: Aα, Bβ, and γ encoded by three …
[HTML][HTML] Heterogeneity of congenital afibrinogenemia, from epidemiology to clinical consequences and management
A Casini, M Neerman-Arbez, P De Moerloose - Blood Reviews, 2021 - Elsevier
Fibrinogen is a complex protein playing a major role in coagulation. Congenital
afibrinogenemia, characterized by the complete absence of fibrinogen, is associated with …
afibrinogenemia, characterized by the complete absence of fibrinogen, is associated with …
Gallium‐Based Liquid Metals: Optical Properties, Applications, and Challenges
Originating from the intrinsic metallic and liquid natures, gallium‐based liquid metals (Ga‐
based LMs) have been greatly developed in the research of soft electronics, chemical …
based LMs) have been greatly developed in the research of soft electronics, chemical …